5532-7
Deprecated CD8 in Blood
Deprecated
Status Information
- Status
- DEPRECATED
- Reason
- Duplicate
- Comment
- Term was mapped to a DEPRECATED term. Remapped to an ACTIVE one.
| Map-To | Long Common Name | Mapping Guidance |
|---|---|---|
| 8101-8 | CD3+CD8+ (T8 suppressor) cells/cells in Blood |
Part Descriptions
LP68355-4 CD8
CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. It is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells. To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Less-common homodimers of the CD8-α chain are also expressed on some cells. The extracellular IgV-like domain of CD8-α interacts with to the α3 portion of the Class I MHC molecule.[2] This affinity keeps the T cell receptor of the cytotoxic T cell and the target cell bound closely together during antigen-specific activation. Cytotoxic T cells with CD8 surface protein are called CD8+ T cells.
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Source: Wikipedia,
CD8
LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- CD8:
ACnc: Pt: WBC: Qn: - Long Common Name
- Deprecated CD8 in Blood
- Short Name
- Deprecated CD8 WBC-aCnc
- Display Name
- CD8 Qn (WBC)
- Consumer Name Alpha Get Info
- CD8, White blood cells
Part Model Get Info
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.69 (MIN)
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | CD8: |
| el-GR | Greek (Greece) | CD8: Synonyms: ACnc CD8 CELLMARK Pt Qn Αριθμός λευκών αιμοσφαιρίων |
| es-AR | Spanish (Argentina) | CD8: |
| es-ES | Spanish (Spain) | CD8: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | CD8: |
| et-EE | Estonian (Estonia) | CD8: Synonyms: Juhuslik Kvantitatiivne Leukotsüüdid |
| fr-CA | French (Canada) | CD8: |
| fr-BE | French (Belgium) | CD8: |
| fr-FR | French (France) | CD8: |
| it-IT | Italian (Italy) | CD8: Synonyms: Concentrazione Arbitraria Globuli bianchi Modelli di superficie cellulare Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | CD8: Synonyms: witte bloedcellen |
| pl-PL | Polish (Poland) | CD8: Synonyms: CD8 |
| pt-BR | Portuguese (Brazil) | CD8: Synonyms: Arbitrary concentration; |
| ru-RU | Russian (Russian Federation) | CD8: Synonyms: Количественный Произвольная концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | CD8: Synonyms: WBC |
| zh-CN | Chinese (China) | CD8: Synonyms: Leu2 Leu-2 T8 T-8 Tsuppressor WBC; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://