55376-8

Megaloblasts/Leukocytes in Blood by Manual count

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Part Descriptions

LP157588-7 Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP68315-8 Megaloblasts
A megaloblast is an unusually large erythroblast that can be associated with pernicious anemia (Vitamin B12 deficiency) and folic acid deficiency (collectively called megaloblastic anemia). It is differentiated from a normoblast, which is a normally-sized erythroblast. This kind of anemia leads to macrocytes (abnormally large red cells). The cause of this cellular gigantism is an impairment in DNA synthesis which delays nuclear maturation and cell division. Because RNA and cytoplasmic elements are synthesized at a constant rate despite the cells impaired DNA synthesis the cells show nuclear-cytoplasmic asynchrony. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Megaloblast

LOINC Names Get Info

Fully-Specified Name: Megaloblasts/Leukocytes:NFr:Pt:Bld:Qn:Manual count
Long Common Name: Megaloblasts/Leukocytes in Blood by Manual count
Short Name: Megaloblasts NFr Bld Manual
Display Name: Megaloblasts/Leukocytes Manual cnt (Bld)
Consumer Name Alpha Get Info: Megaloblasts/White Blood Cells, Blood

Part Model Get Info

Component
Megaloblasts/Leukocytes
LP445464-3
- Analyte
  Megaloblasts/Leukocytes
  LP445464-3
  - Component Numerator
    Megaloblasts
    LP68315-8
    - Component Numerator Core
      Megaloblasts
      LP68315-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Leukocytes
    LP157588-7
    - Component Denominator Core
      Leukocytes
      LP157588-7
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Manual count
LP6377-8

Basic Attributes

Class: HEM/BC
Type: Laboratory
First Released: Version 2.27
Last Updated: Version 2.79 (NAM)
Change Reason: Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Megaloblasty/100 leukocytů:Početní podíl:Časový bod:Krev:Kvantitativní:Počítání manuálně
el-GR	Greek (Greece)	Μεγαλοβλάστες/Λευκοκύτταρα:NFr:Pt:Αίμα:Qn:Χειροκίνητη καταμέτρηση Synonyms: HEM/BC NFr Pt Qn Αίμα Λευκοκύτταρα Μεγαλοβλάστες Μη αυτόματη Χειροκίνητη καταμέτρηση
es-ES	Spanish (Spain)	Megaloblastos/Leucocitos:Fracción numérica:Punto temporal:Sangre:Qn:Contaje manual Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Megaloblastos / 100 leucocitos:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Conteo manual
fr-CA	French (Canada)	Mégaloblastes/Leucocytes:Fraction numérique:Temps ponctuel:Sang:Quantitatif:Numération manuelle
fr-FR	French (France)	Mégaloblastes/leucocytes:Fraction de nombres:Ponctuel:Sang:Numérique:Comptage manuel
it-IT	Italian (Italy)	Megaloblasti/Leucociti:NFr:Pt:Sangue:Qn:Conta manuale Synonyms: Ematologia (coagulazione) conta differenziale Frazione numerica Punto nel tempo (episodio) Sangue
nl-NL	Dutch (Netherlands)	megaloblasten/leukocyten:getalsfractie:moment:bloed:kwantitatief:manuele telling Synonyms: handmatige methode handmatige telling
pl-PL	Polish (Poland)	Megaloblasty/leukocyty:frakcja liczbowa:punkt w czasie:krew:ilościowy:zliczanie ręczne Synonyms: Leukocyty
pt-BR	Portuguese (Brazil)	Megaloblastos/100 leucócitos:#N/A:Pt:SgTotal:Qn:Contagem manual Synonyms: ; Leucoc; White blood cell; Leuc; Leuk; Leukocyte; Lkcs; White blood cells; Leucocs; 100Leucoc; Fr; Number fraction; Percent; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Manl; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
ru-RU	Russian (Russian Federation)	Мегалобласты/Лейкоциты:КолДоля:ТчкВрм:Кр:Колич:Ручной подсчет Synonyms: Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR	Turkish (Turkey)	Megaloblast/Lökosit:SayFr:Zmlı:Kan:Kant:Manuel sayım Synonyms: El ile
zh-CN	Chinese (China)	巨成红细胞/白细胞:计数型分数:时间点:全血:定量型:手工计数方法 Synonyms: Leuc;Leuk;Lkcs;WBC;WBCs;白细胞;White blood cell;WBC;白细胞类;白细胞类髓系细胞;白血球;白血细胞;白细胞数人工计数;人工计数方法;人工计数法;手工计数;手工计数法可用数量表示的;定量性;数值型;数量型;连续数值型标尺实验室手工方法;手工;手工法;手工类实验室方法;手工类方法;手工类检验方法幼巨红细胞;巨母红细胞;巨成红;幼巨红;巨母红数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间血;血液血液学/细胞计数;血液学与细胞计数

Example Units

Unit	Source
%	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=55376-8

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.