56248-8

Dog dander IgG4 Ab [Mass/volume] in Serum

Active

Part Descriptions

LP13938-3 Dog dander
The dominant allergen in dog epithelium (e2). Dog dander (e5), however, contains several allergens such as albumin and other serum proteins, and is thus a more sensitive test. Source: Regenstrief Institute

LP13938-3 Dog dander
Dander is the material shed by the Dog into the environment through hair and "dandruff". Dander is the "end product" and by far the most common source of Dog allergens and contains the highest proportion of dog specific allergens. It has naturally figured very prominently in clinical research, but all three allergen sources are important for an understanding of Dog allergy.

Dog dander clearly represents an important source of inhalant allergens, and many studies report that Dog may frequently induce symptoms in sensitised individual. Symptoms include asthma, allergic rhinitis and allergic conjunctivitis. Copyright Copyright © 2006 Phadia AB. Source: ImmunoCap, ImmunoCap

LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Dog dander Ab.IgG4:MCnc:Pt:Ser:Qn:
Long Common Name: Dog dander IgG4 Ab [Mass/volume] in Serum
Short Name: Dog Dander IgG4-mCnc
Display Name: Dog dander IgG4 (S) [Mass/Vol]
Consumer Name Alpha Get Info: Dog dander IgG4 antibody

Part Model Get Info

Component
Dog dander Ab.IgG4
LP95684-4
- Analyte
  Dog dander Ab.IgG4
  LP95684-4
  - Component Numerator
    Dog dander Ab.IgG4
    LP95684-4
    - Component Numerator Core
      Dog dander
      LP13938-3
    - Component Numerator Core Suffix
      Ab.IgG4
      LP32397-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: ALLERGY
Type: Laboratory
First Released: Version 2.29
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 13852

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Pes lupy IgG4:Hmotnostní koncentrace:Časový bod:Sérum:Kvantitativní:
el-GR	Greek (Greece)	Πιτυρίδα σκύλου Ab.IgG4:MCnc:Pt:Ορός:Qn: Synonyms: Ab.IgG4 ALLERGY MCnc Pt Qn Αντίσωμα Ορός Πιτυρίδα σκύλου
es-MX	Spanish (Mexico)	Caspa de perro Ab.IgG4:Concentración de masa:Punto temporal:Suero:Cuantitativo:
es-ES	Spanish (Spain)	Caspa de perro IgG4:Concentración de masa:Punto temporal:Suero:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Koera kõõm antikehad.IgG4:MCnc:Pt:S:Qn: Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Squames de chien, IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-FR	French (France)	Chien (squames) Ac IgG4:Masse/Volume:Ponctuel:Sérum:Numérique:
fr-BE	French (Belgium)	Squames de chien Anticorps. IgG4:Concentration de masse:Temps ponctuel:Sérum:Quantitatif: Synonyms: Anticorps Squames de chien,e5
it-IT	Italian (Italy)	Cane, forfora Ab.IgG4:MCnc:Pt:Siero:Qn: Synonyms: Anticorpi IgG4 anticorpo Concentrazione di Massa Forfora di cane Punto nel tempo (episodio) Risposta agli antigeni Siero
nl-NL	Dutch (Netherlands)	hondenroos As.IgG4:massa/volume:moment:serum:kwantitatief: Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Łupież psa Ab.IgG4:stężenie masowe:punkt w czasie:surowica:ilościowy: Synonyms: łupież psi Przeciwciało do sierści psa Przeciwciało IgG4 do sierści psa
pt-BR	Portuguese (Brazil)	Caspa de cão Ac.IgG4:#N/A:Pt:Soro:Qn: Synonyms: Dog hair; e005; e5; Canine; Mass concentration; Level; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; ALLERGY TESTING; Allergens; Allergen
ru-RU	Russian (Russian Federation)	Собачья перхоть Ат.IgG4:МассКонц:ТчкВрм:Сыв:Колич: Synonyms: Антитело Количественный Массовая концентрация Собака перхоть Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Köpek deri döküntüsü Ab.IgG4:KütlKons:Zmlı:Ser:Kant: Synonyms: Ak Ak.IgG4 Köpek kepeği
zh-CN	Chinese (China)	狗毛屑抗体.IgG4:质量浓度:时间点:血清:定量型: Synonyms: Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 犬科狗毛屑 Ab 狗毛屑（毛皮屑、皮屑、皮毛屑）

Example Units

Unit	Source
ug/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=56248-8

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.