58361-7

Norbuprenorphine/Creatinine [Mass Ratio] in Urine

Active

Part Descriptions

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP34568-3 Norbuprenorphine
Buprenorphine (tradename Buprenex), is a long-lasting, high affinity opioid that acts on the same receptors as heroin and morphine but does not produce the same intense high or dangerous side effects. It is used for the treatment of pain and opioid dependence. The major buprenorphine metabolites are norbuprenorphine, buprenorphine-3-glucuronide (B3G), and norbuprenorphine-3-glucuronide (N3G). The analysis of buprenorphine and metabolites is performed to monitor compliance to drug therapy. Source: Regenstrief LOINC

LP34568-3 Norbuprenorphine
Norbuprenorphine is the primary active metabolite of buprenorphine, and its mean steady-state plasma concentration is comparable to or even exceeds that of buprenorphine following sublingual buprenorphine absorption (Kuhlman et al., 1998). It is likely to contribute to the overall pharmacological effects of buprenorphine. Buprenorphine and norbuprenorphine displayed distinct pharmacological properties at mu-opioid, delta-opioid, and kappa-opioid receptors and the ORL1 receptor. PMID: 11303059 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Norbuprenorphine/Creatinine:MRto:Pt:Urine:Qn:
Long Common Name: Norbuprenorphine/Creatinine [Mass Ratio] in Urine
Short Name: Norbuprenorphine/Creat Ur
Display Name: Norbuprenorphine/Creatinine (U) [Mass ratio]
Consumer Name Alpha Get Info: Norbuprenorphine/Creatinine, Urine

Part Model Get Info

Component
Norbuprenorphine/Creatinine
LP286675-6
- Analyte
  Norbuprenorphine/Creatinine
  LP286675-6
  - Component Numerator
    Norbuprenorphine
    LP34568-3
    - Component Numerator Core
      Norbuprenorphine
      LP34568-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MRto
LP6834-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.30
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 2091

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Norbuprenorfin/kreatinin:Hmotnostní poměr:Časový bod:Moč:Kvantitativní:
el-GR	Greek (Greece)	Νορβουπρενορφίνη/Κρεατινίνη:MRto:Pt:Ούρα:Qn: Synonyms: DRUG/TOX MRto Pt Qn Κρεατινίνη Νορβουπρενορφίνη Ούρα
es-ES	Spanish (Spain)	Norbuprenorfina/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Norbuprenorfina / Creatinina:Relación de masa:Punto temporal:Orina:Cuantitativo:
et-EE	Estonian (Estonia)	Norbuprenorfiin/kreatiniin:MRto:Pt:U:Qn: Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CA	French (Canada)	Norbuprénorphine/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
fr-FR	French (France)	Norbuprénorphine/créatinine:Masse ratio:Ponctuel:Urine:Numérique:
fr-BE	French (Belgium)	Norbuprenorphine/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif: Synonyms: Rapport de masse
it-IT	Italian (Italy)	Norbuprenorfina/Creatinina:MRto:Pt:Urine:Qn: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa
nl-NL	Dutch (Netherlands)	norbuprenorfine/creatinine:massaverhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pt-BR	Portuguese (Brazil)	Norbuprenorfina/Creatinina:#N/A:Pt:Urina:Qn: Synonyms: norBUP; Buprenorphine metAcolite; NBU; Creat; CR; mRto; Mass concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY; UCr
ru-RU	Russian (Russian Federation)	Норбупренорфин/Креатинин:МассОтн:ТчкВрм:Моча:Колич: Synonyms: Количественный Масс отношение Точка во времени;Момент
tr-TR	Turkish (Turkey)	Norbuprenorfin/Kreatinin:KütlOr:Zmlı:İdrar:Kant:
zh-CN	Chinese (China)	去甲基丁丙诺啡/肌酐:质量比率:时间点:尿液:定量型: Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 UCr 可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间来自于同一体系的两种分析物的质量之比;质量比毒品毒品类肌酸内酰胺脱甲基丁丙诺啡;丁丙诺啡代谢产物;去甲丁丙诺啡;去甲基布诺啡;去甲布诺啡药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ug/g{creat}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.