59069-5

Nuclear Ab [Presence] in Serum by Hep2 substrate

Active

Part Descriptions

LP16670-9   Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
PMID: 24563360 Source: Regenstrief LOINC

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs), also known as anti-nuclear factor or ANF, are auto-antibodies directed against contents of the cell nucleus. They are present in low numbers in the general population but higher than normal amounts in autoimmune diseases, including lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, scleroderma, and autoimmune hepatitis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Anti-nuclear antibodies

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are autoantibodies directed against contents of the cell nucleus. They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.

The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as[citation needed] Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component

Nuclear Ab

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

Hep2 substrate

Additional Names

Short Name

ANA Ser Ql HEp2 subst

Display Name

Nuclear Ab Hep2 substrate Ql (S)

Consumer Name Alpha Get Info

Nuclear antibody, Blood

Basic Attributes

Class

SERO

Type

Laboratory

First Released

Version 2.32

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

6047

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• ANA
• ANF
• Antby
• Anti
• Antibodies
• Antibody
• Antinuclear antibody
• Autoantibodies
• Autoantibody
• NA
• Nuc
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serology
• Serum
• SR

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59069-5

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.