59252-7

Homocysteine cysteine disulfide [Moles/volume] in Cerebrospinal Fluid

Active

Part Description

LP30736-0 Homocysteine cysteine disulfide
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocystine and homocysteine-cysteine mixed disulfide account for >98% of total homocysteine in plasma from healthy individuals. PMID: 11592966 Oxidation of low-density lipoprotein (LDL) is thought to be a major factor in the pathophysiology of atherosclerosis. Elevated plasma homocysteine is an accepted risk factor for atherosclerosis, and may act through LDL oxidation, although this is controversial. However, the major thiol in plasma is cysteine, which is present at concentrations approximately 10 times greater than homocysteine; therefore homocystine in plasma is insignificant, and consequently homocystine is unlikely to influence LDL oxidation in vivo. PMID: 14732479 Increasing evidence supports a role for an elevation of homocysteine in schizophrenia. It has been demonstrated that neural tube defects are related to a genetic defect in homocysteine metabolism. Sufficient intake of folic acid is believed to reduce this risk by enhancing methylation of homocysteine and its conversion to methionine, thereby compensating for this genetic defect. Plasma homocysteine levels are elevated when folate levels are in the lower half of the normal range. PMID: 16143442 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database,

LOINC Names Get Info

Fully-Specified Name: Homocysteine cysteine disulfide:SCnc:Pt:CSF:Qn:
Long Common Name: Homocysteine cysteine disulfide [Moles/volume] in Cerebrospinal Fluid
Short Name: Hycs-Cys diS CSF-sCnc
Display Name: Homocysteine cysteine disulfide (CSF) [Moles/Vol]
Consumer Name Alpha Get Info: Homocysteine cysteine disulfide, Spinal fluid

Part Model Get Info

Component
Homocysteine cysteine disulfide
LP30736-0
- Analyte
  Homocysteine cysteine disulfide
  LP30736-0
  - Component Numerator
    Homocysteine cysteine disulfide
    LP30736-0
    - Component Numerator Core
      Homocysteine cysteine disulfide
      LP30736-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.32
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Homocystein-cystein-disulfid:Látková koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:
el-GR	Greek (Greece)	Δισουλφιδικός δεσμός κυστεΐνης-ομοκυστεΐνης:SCnc:Pt:ΕΝΥ:Qn: Synonyms: CHEM Pt Qn SCnc Δισουλφιδικός δεσμός κυστεΐνης-ομοκυστεΐνης ΕΝΥ Κυστεΐνη Ομοκυστεΐνη
es-ES	Spanish (Spain)	Homocisteína cisteína disulfuro:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Disulfuro de cisteína de homocisteína:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-CA	French (Canada)	Bisulfure de cystéine homocystéine:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
fr-FR	French (France)	Homocystéine cystéine disulfide:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-BE	French (Belgium)	Bisulfure de cystéine homocystéine:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
it-IT	Italian (Italy)	Omocisteina cisteina, disolfuro:SCnc:Pt:LCS:Qn: Synonyms: Chimica Concentrazione di Sostanza Disolfuro omocisteina cisteina Liquido cerebrospinale Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	homocysteïne cysteïne disulfide:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pl-PL	Polish (Poland)	Homocysteina cysteina disiarczek:stężenie molowe:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy: Synonyms: Disiarczek homocysteiny-cysteiny;Wiązanie disiarczkowe cysteiny i homocysteiny
ru-RU	Russian (Russian Federation)	Гомоцистеин цистеин дисульфид:МолКонц:ТчкВрм:ЦСЖ:Колич: Synonyms: Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Homosistein sistein disülfür:SubKons:Zmlı:BOS:Kant:
zh-CN	Chinese (China)	同型半胱氨酸-半胱氨酸二硫化物:物质的量浓度:时间点:脑脊液:定量型: Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Cys;巯基丙氨酸 HCY;Hcys;Hcyst;巯基丁氨酸;高半胱氨酸 Hcys-Cys diS;Hcys-Cys 二硫化物;巯基丁氨酸-巯基丙氨酸二硫化物克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液

Example Units

Unit	Source
umol/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.