Version 2.77

Part Description

LP100046-4   Ramelteon M-II
The major metabolite of ramelteon, M-II, is active and has approximately one tenth and one fifth the binding affinity of the parent molecule for the human MT1 and MT2 receptors, respectively, and is 17 - 25-fold less potent than ramelteon in in vitro functional assays. Although the potency of M-II at MT1 and MT2 receptors is lower than the parent drug, M-II circulates at higher concentrations than the parent producing 20 - 100 fold greater mean systemic exposure when compared to ramelteon. M-II has weak affinity for the serotonin 5-HT2B receptor, but no appreciable affinity for other receptors or enzymes. Similar to ramelteon, M-II does not interfere with the activity of a number of endogenous enzymes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ramelteon M-II

Fully-Specified Name

Component
Ramelteon M-II
Property
MCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
Ramelteon M-II Bld-mCnc
Display Name
Ramelteon M-II (Bld) [Mass/Vol]
Consumer Name Alpha Get Info
Ramelteon M-II, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG24767-2 Ramelteon M-II|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Ramelteon M-II:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
es-ES Spanish (Spain) Ramelteon M-II:Concentración de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Ramelteoon M2:MCnc:Pt:B:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Ramelteon M-II:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FR French (France) Rameltéon M-II:Masse/Volume:Ponctuel:Sang:Numérique:
fr-BE French (Belgium) Ramelteon M-II:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
it-IT Italian (Italy) Ramelteon M-II:MCnc:Pt:Sangue:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) ramelteon M-II:massa/volume:moment:bloed:kwantitatief:
pt-BR Portuguese (Brazil) Ramelteon M-II::Pt:SgTotal:Qn:
ru-RU Russian (Russian Federation) Рамелтеон M-II:МассКонц:ТчкВрм:Кр:Колич:
Synonyms: Количественный Кровь Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Ramelteon M-II:KütlKons:Zmlı:Kan:Kant:
zh-CN Chinese (China) 雷美替胺 M-II:质量浓度:时间点:全血:定量型:
Synonyms: M 型 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 瑞美替昂 M-II;雷美替胺代谢产物;雷美替胺代谢物 瑞美替昂;(S)-N-(2-(1,6,7,8-四氢-2H-茚并(5,4-b)呋喃-8-基)乙基)丙酰胺;瑞美替胺;Ramelteon;Rozerem;N-{2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]fur-8-yl]ethyl}propanamid;N-{2-[(8S)-1,6,7,8-tétrahydro-2H-indéno[5,4-b]fur-8-yl]éthyl}propanamide;N-{2-[(8S)-1,6,7,8-Tetrahydro-2H-in 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59313-7