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Part Description

LP100046-4   Ramelteon M-II
The major metabolite of ramelteon, M-II, is active and has approximately one tenth and one fifth the binding affinity of the parent molecule for the human MT1 and MT2 receptors, respectively, and is 17 - 25-fold less potent than ramelteon in in vitro functional assays. Although the potency of M-II at MT1 and MT2 receptors is lower than the parent drug, M-II circulates at higher concentrations than the parent producing 20 - 100 fold greater mean systemic exposure when compared to ramelteon. M-II has weak affinity for the serotonin 5-HT2B receptor, but no appreciable affinity for other receptors or enzymes. Similar to ramelteon, M-II does not interfere with the activity of a number of endogenous enzymes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ramelteon M-II

LOINC Names Get Info

Fully-Specified Name
Ramelteon M-II:MCnt:Pt:Tiss:Qn:
Long Common Name
Ramelteon M-II [Mass/mass] in Tissue
Short Name
Ramelteon M-II Tiss-mCnt
Display Name
Ramelteon M-II (Tiss) [Mass/Mass]
Consumer Name Alpha Get Info
Ramelteon M-II, Tissue

Part Model Get Info

  • Component
    Ramelteon M-II
    LP100046-4
    • Analyte
      Ramelteon M-II
      LP100046-4
      • Component Numerator
        Ramelteon M-II
        LP100046-4
        • Component Numerator Core
          Ramelteon M-II
          LP100046-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnt
    LP6828-0
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.70 (MIN)
Change Reason
Changed Property from 'MCnc' it fit the current LOINC model.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Ramelteon M-II:Hmotnostní obsah:Časový bod:Tkáně a stěry:Kvantitativní:
el-GRGreek (Greece)Ραμελτεόνη M-II:MCnt:Pt:Ιστός:Qn:
Synonyms: DRUG/TOX M MCnt Pt Qn Ιστός Ραμελτεόνη Ραμελτεόνη M-II
es-MXSpanish (Mexico)Ramelteon M-II:Contenido masivo:Punto temporal:Tejido y frotis:Cuantitativo:
es-ESSpanish (Spain)Ramelteon M-II:Contenido de masa:Punto temporal:Tejido:Qn:
Synonyms: Cuantitativo
et-EEEstonian (Estonia)Ramelteoon M2:MCnt:Pt:Tis:Qn:
Synonyms: Juhuslik Kude Kvantitatiivne
fr-CAFrench (Canada)Ramelteon M-II:Contenu de masse:Temps ponctuel:Tissu:Quantitatif:
fr-FRFrench (France)Rameltéon M-II:Masse/Masse:Ponctuel:Tissu:Numérique:
fr-BEFrench (Belgium)Ramelteon M-II:Contenu de masse:Temps ponctuel:Tissu:Quantitatif:
it-ITItalian (Italy)Ramelteon M-II:MCnt:Pt:Tessuto:Qn:
Synonyms: Contenuto di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Tessuto & Strisci
nl-NLDutch (Netherlands)ramelteon M-II:massa/massa:moment:weefsel en uitstrijkjes:kwantitatief:
pl-PLPolish (Poland)Ramelteon M-II:zawartość masowa:punkt w czasie:tkanka i rozmazy:ilościowy:
Synonyms: Ramelteon metabolit M-II
ru-RURussian (Russian Federation)Рамелтеон M-II:МассСод:ТчкВрм:Тк:Колич:
Synonyms: Количественный Масса содержание Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)Ramelteon M-II:Kütlİçrk:Zmlı:Doku:Kant:
zh-CNChinese (China)雷美替胺 M-II:质量含量:时间点:组织与涂片:定量型:
Synonyms: M 型 单位质量的质量数;质量含量(单位质量) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 毒品 毒品类 瑞美替昂 M-II;雷美替胺代谢产物;雷美替胺代谢物 瑞美替昂;(S)-N-(2-(1,6,7,8-四氢-2H-茚并(5,4-b)呋喃-8-基)乙基)丙酰胺;瑞美替胺;Ramelteon;Rozerem;N-{2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]fur-8-yl]ethyl}propanamid;N-{2-[(8S)-1,6,7,8-tétrahydro-2H-indéno[5,4-b]fur-8-yl]éthyl}propanamide;N-{2-[(8S)-1,6,7,8-Tetrahydro-2H-in 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

UnitSource
ng/gExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59319-4