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Part Description

LP100046-4   Ramelteon M-II
The major metabolite of ramelteon, M-II, is active and has approximately one tenth and one fifth the binding affinity of the parent molecule for the human MT1 and MT2 receptors, respectively, and is 17 - 25-fold less potent than ramelteon in in vitro functional assays. Although the potency of M-II at MT1 and MT2 receptors is lower than the parent drug, M-II circulates at higher concentrations than the parent producing 20 - 100 fold greater mean systemic exposure when compared to ramelteon. M-II has weak affinity for the serotonin 5-HT2B receptor, but no appreciable affinity for other receptors or enzymes. Similar to ramelteon, M-II does not interfere with the activity of a number of endogenous enzymes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ramelteon M-II

LOINC Names Get Info

Fully-Specified Name
Ramelteon M-II:MCnc:Pt:Urine:Qn:
Long Common Name
Ramelteon M-II [Mass/volume] in Urine
Short Name
Ramelteon M-II Ur-mCnc
Display Name
Ramelteon M-II (U) [Mass/Vol]
Consumer Name Alpha Get Info
Ramelteon M-II, Urine

Part Model Get Info

  • Component
    Ramelteon M-II
    LP100046-4
    • Analyte
      Ramelteon M-II
      LP100046-4
      • Component Numerator
        Ramelteon M-II
        LP100046-4
        • Component Numerator Core
          Ramelteon M-II
          LP100046-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Ramelteon M-II:Hmotnostní koncentrace:Časový bod:Moč:Kvantitativní:
el-GRGreek (Greece)Ραμελτεόνη M-II:MCnc:Pt:Ούρα:Qn:
Synonyms: DRUG/TOX M MCnc Pt Qn Ούρα Ραμελτεόνη Ραμελτεόνη M-II
es-ESSpanish (Spain)Ramelteon M-II:Concentración de masa:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Ramelteon M-II:Concentración de masa:Punto temporal:Orina:Cuantitativo:
et-EEEstonian (Estonia)Ramelteoon M2:MCnc:Pt:U:Qn:
Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CAFrench (Canada)Ramelteon M-II:Concentration de masse:Temps ponctuel:Urine:Quantitatif:
fr-FRFrench (France)Rameltéon M-II:Masse/Volume:Ponctuel:Urine:Numérique:
fr-BEFrench (Belgium)Ramelteon M-II:Concentration de masse:Temps ponctuel:Urine:Quantitatif:
it-ITItalian (Italy)Ramelteon M-II:MCnc:Pt:Urine:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NLDutch (Netherlands)ramelteon M-II:massa/volume:moment:urine:kwantitatief:
pl-PLPolish (Poland)Ramelteon M-II:stężenie masowe:punkt w czasie:mocz:ilościowy:
Synonyms: Ramelteon metabolit M-II
ru-RURussian (Russian Federation)Рамелтеон M-II:МассКонц:ТчкВрм:Моча:Колич:
Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)Ramelteon M-II:KütlKons:Zmlı:İdrar:Kant:
zh-CNChinese (China)雷美替胺 M-II:质量浓度:时间点:尿液:定量型:
Synonyms: M 型 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 瑞美替昂 M-II;雷美替胺代谢产物;雷美替胺代谢物 瑞美替昂;(S)-N-(2-(1,6,7,8-四氢-2H-茚并(5,4-b)呋喃-8-基)乙基)丙酰胺;瑞美替胺;Ramelteon;Rozerem;N-{2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]fur-8-yl]ethyl}propanamid;N-{2-[(8S)-1,6,7,8-tétrahydro-2H-indéno[5,4-b]fur-8-yl]éthyl}propanamide;N-{2-[(8S)-1,6,7,8-Tetrahydro-2H-in 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

UnitSource
ng/mLExample UCUM Units

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59321-0