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Part Description

LP28735-6   DNA index
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190 Source: Regenstrief LOINC, PMID: 24532190

LOINC Names Get Info

Fully-Specified Name
DNA index:AreaRto:Pt:Cells.XXX:Qn:Automated image cytometry
Long Common Name
DNA index by Automated image cytometry
Short Name
DNA Index Auto cyto
Display Name
DNA index Automated image cytometry (Unsp Cells) [Area ratio]
Consumer Name Alpha Get Info
DNA index, Unspecified Cells

Part Model Get Info

  • Component
    DNA index
    LP28735-6
    • Analyte
      DNA index
      LP28735-6
      • Component Numerator
        DNA index
        LP28735-6
        • Component Numerator Core
          DNA index
          LP28735-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    AreaRto
    LP6783-7
  • Time
    Pt
    LP6960-1
  • System
    Cells.XXX
    LP100478-9
  • Scale
    Qn
    LP7753-9
  • Method
    Automated image cytometry
    LP100479-7

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.73 (MIN)
Change Reason
Based on original communication regarding this term, the component was edited.
Order vs. Observation
Both
Common Test Rank Get Info
11821

Formula (Readable)

DNA index = DNA abnormal cell/DNA normal cell

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)DNA index:Poměr plochy:Časový bod:Buňky.XXX:Kvantitativní:Obrazová cytometrie automatizovaně
el-GRGreek (Greece)Δείκτης DNA:AreaRto:Pt:Κύτταρα.XXX:Qn:Αυτόματη κυτταρομετρία εικόνας
Synonyms: AreaRto DNA MOLPATH Pt Qn XXX Αυτόματη Αυτόματη κυτταρομετρία εικόνας Δείκτης DNA Κύτταρα.XXX
es-ESSpanish (Spain)Índice del ADN:Relacion de superficie:Punto temporal:Células XXX:Qn:Citometría de imagen automatizada
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Índice de ADN:Relación de área:Punto temporal:Cells.XXX:Cuantitativo:Citometría de imagen automatizada
fr-FRFrench (France)ADN index:Aire ratio:Ponctuel:Cellules XXX:Numérique:Cytométrie en image automatique
it-ITItalian (Italy)DNA, indice:AreaRto:Pt:Cellule.XXX:Qn:Citometria automatizzata immagine
Synonyms: Indice di DNA Patologia molecolare Punto nel tempo (episodio) Rapporto Area
nl-NLDutch (Netherlands)DNA index:oppervlakteverhouding:moment:cellen.XXX:kwantitatief:geautomatiseerde beeldcytometrie
pl-PLPolish (Poland)DNA indeks:współczynnik powierzchni:punkt w czasie:komórki.XXX:ilościowy:zautomatyzowana cytometria obrazowa
Synonyms: Kwas deoksyrybonukleinowy Wskaźnik ilości DNA w komórce nowotworowej
tr-TRTurkish (Turkey)DNA indeksi:AlanOran:Zmlı:Hücreler.XXX:Kant:Otomatize görüntü sitometri
zh-CNChinese (China)DNA 指数:面积比率:时间点:细胞.XXX:定量型:自动化图像细胞仪
Synonyms: DI;DNA 指数 = 肿瘤 G1 峰的平均通道数（mean channel #）与正常细胞平均通道数之比;DNA 指数（DNA index，DI） XXX细胞;此处不作说明的细胞;细胞.此处不作说明的;此处未作说明的细胞 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 全自动图像细胞仪;全自动细胞图像分析系统 分子病理学;分子病理学试验 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于同一体系的两个面积之比;面积比;面积比值 电子化 自动 自动型 自动法;自动化

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