Version 2.78

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
LA

Additional Names

Short Name
CMV Ab SerPl Ql LA
Display Name
CMV Ab LA Ql
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Latexagglutination
Synonyms: CMV
es-ES Spanish (Spain) Citomegalovirus Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:Aglutinación de latex
es-MX Spanish (Mexico) Citomegalovirus Ab:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Aglutinación de látex
et-EE Estonian (Estonia) Tsütomegaloviirus antikehad:PrThr:Pt:S/P:Ord:LA
Synonyms: Järgarvuline Juhuslik Lateksaglutinatsioon Plasma Seerum Seerum või plasma
fr-CA French (Canada) Cytomégalovirus, Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Agglutination au latex
fr-FR French (France) Cytomégalovirus Ac:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Agglutination latex
fr-BE French (Belgium) Cytomégalovirus Ac:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Agglutination au latex
Synonyms: Anticorps CMV
it-IT Italian (Italy) Citomegalovirus Ab:PrThr:Pt:Siero/Plasma:Ord:LA
Synonyms: Agglutinazione al lattice anticorpo Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) Cytomegalovirus As:aanwezigheid:moment:serum of plasma:ordinaal:latexagglutinatie
Synonyms: antistof; antilichaam LA
pl-PL Polish (Poland) Wirus cytomegalii Ab:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:aglutynacja lateksowa
Synonyms: Cytomegalowirus Przecwciała do cytomegalowirusa
pt-BR Portuguese (Brazil) Citomegalovírus Ac::Pt:Soro/Plas:Ord:Lâmina
ru-RU Russian (Russian Federation) Цитомегаловирус Ат:PrThr:ТчкВрм:Сыв/Плаз:Пор:ЛА
Synonyms: Антитело Латекс-агглютинация Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus Ab:MevcEşik:Zmlı:Ser/Plaz:Srl:LA
Synonyms: Ak Mevcut
zh-CN Chinese (China) 巨细胞病毒 抗体:存在情况或阈值:时间点:血清/血浆:序数型:胶乳凝集试验法
Synonyms: Ab;自身抗体 CMV Ab CMV 抗体 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 乳胶凝集试验;凝集试验.胶乳;凝集试验法.胶乳;胶乳凝集试验;胶乳颗粒凝集;胶乳颗粒凝集法;胶乳颗粒凝集试验;胶乳颗粒凝集试验法;颗粒凝集.胶乳;颗粒凝集法.胶乳;颗粒凝集试验.胶乳;颗粒凝集试验法.胶乳 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 巨细胞病毒 Ab 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=59838-3