60550-1

Fascin Ag [Presence] in Tissue by Immune stain

Active

Part Description

LP101504-1 Fascin
Fascin is a actin cross-linking protein. It is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates, including humans. Fascin is spaced at 11 nanometre intervals along the filament. The bundles in cross section are seen to be hexagonally packed, and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins. It is calcium insensitive and monomeric.

Fascin binds beta-catenin, and colocalizes with it at the leading edges and borders of epithelial and endothelial cells. The role of Fascin in regulating cytoskeletal structures for the maintenance of cell adhesion, coordinating motility and invasion through interactions with signalling pathways is an active area of research especially from the cancer biology perspective. Abnormal fascin expression or function has been implicated in breast cancer, colon cancer, esophageal squamous cell carcinoma, gallbladder cancer and prostate cancer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name: Fascin Ag:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name: Fascin Ag [Presence] in Tissue by Immune stain
Short Name: Fascin Ag Tiss Ql ImStn
Display Name: Fascin Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info: Fascin antigen, Tissue

Part Model Get Info

Component
Fascin Ag
LP450036-1
- Analyte
  Fascin Ag
  LP450036-1
  - Component Numerator
    Fascin Ag
    LP450036-1
    - Component Numerator Core
      Fascin
      LP101504-1
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Immune stain
LP6333-1

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.34
Last Updated: Version 2.82 (NAM)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 13880

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fascin:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GR	Greek (Greece)	Φασκίνη Αντιγόνο:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση Synonyms: Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Ιστός Φασκίνη
es-ES	Spanish (Spain)	Fascina Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Fascin:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
et-EE	Estonian (Estonia)	Fastsiin antigeen:PrThr:Pt:Tis:Ord:Immuunvärv Synonyms: Järgarvuline Juhuslik Kude
fr-FR	French (France)	Fascine Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-IT	Italian (Italy)	Fascina, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica Synonyms: Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NL	Dutch (Netherlands)	fascine Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring Synonyms: antigeen
pl-PL	Polish (Poland)	Fascyna Ag:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:barwienie immunohistochemiczne
ru-RU	Russian (Russian Federation)	Фасцин Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	Faskin Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama Synonyms: Antijen Mevcut
zh-CN	Chinese (China)	肌成束蛋白抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法 Synonyms: Ag Fascin 蛋白;Actin 束蛋白;细胞骨架蛋白依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染法染色方法染色法着色着色方法着色法

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.