63217-4
Cyclic citrullinated peptide IgG Ab [Units/volume] in Body fluid by Immunoassay
Active
Part Descriptions
LP29176-2 Cyclic citrullinated peptide
Citrullinated peptide (CCP) is a naturally occurring protein that is produced during the metabolism of ornithine to arginine. CCP proteins are found in synovial tissue of patients with rheumatoid arthritis (RA). High levels of antibodies to CCP have a strong association with RA and are predictive of an aggressive and destructive disease outcome. CCP antibody tests can help diagnose RA when the rheumatoid factor (RF) is negative or below 50 IU/mL.(Pagana, Kathleen Deska, and Timothy James Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. St. Louis, MO: Mosby/Elsevier, 2014. Print.) .) IgA to CCP is more elevated in patients with RA than levels found in healthy individuals or those with other rheumatic diseases. PMID: 18565246
Source: Regenstrief LOINC
LP37860-1 Cyclic citrullinated peptide Ab.IgG
Citrulline is a non-standard amino acid that can be incorporated into proteins only by modification of arginine during a variety of biologic processes including inflammation. Several citrullinated proteins have been demonstrated in the RA synovium. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 0.3 to 1% worldwide and leads to progressive joint erosion and disability if not treated early. Identifying citrullinated epitopes targets led to first and then second generation anti-cyclic citrullinated peptide (anti-CCP) antibody assays. These anti-CCP antibodies are important diagnostic and prognostic markers for rheumatoid arthritis (RA) as they: 1) may be more sensitive than RF (rheumatoid factor) in early and established disease, 2) may be a marker of erosive disease, and 3) may be found in healthy patients years prior to clinical onset, and 4) may predict development of undifferentiated arthritis into RA. PMID: 19427413 PMID: 17558653
Source: Regenstrief LOINC, PMID: 19427413
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cyclic citrullinated peptide Ab.IgG
- Property
- ACnc
- Time
- Pt
- System
- Body fld
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- cCP IgG Fld IA-aCnc
- Display Name
- Cyclic citrullinated peptide IgG IA Qn (Body fld)
- Consumer Name Alpha Get Info
- Cyclic citrullinated peptide IgG antibody, Body fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.73
- Change Reason
- The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7146
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Κυκλικό κιτρουλλινιωμένο πεπτίδιο IgG ανοσοσφαιρίνη: Synonyms: Ab IgG |
| es-ES | Spanish (Spain) | Peptido cíclico citrulinado IgG: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Péptido cíclico citrulinado Ab.IgG: |
| et-EE | Estonian (Estonia) | Tsükliline tsitrulleeritud peptiid antikehad.IgG: Synonyms: Immuunglobuliin G Juhuslik Kehavedelik Kvantitatiivne |
| fr-CA | French (Canada) | Peptide citrulliné cyclique, IgG: |
| fr-FR | French (France) | Peptide cyclique citrulliné anticorps IgG: |
| fr-BE | French (Belgium) | Peptide citrulliné cyclique Anticorps. IgG: Synonyms: Anticorps CCP |
| it-IT | Italian (Italy) | Peptide ciclico citrullinato Ab.IgG: Synonyms: anticorpi IgG anticorpo CCP Concentrazione Arbitraria Immunoassay Liquido corporeo Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | cyclisch citrulline-peptide As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | Циклический цитруллинизированный пептид Ат.IgG: Synonyms: Антитело Количественный Произвольная концентрация Тела жидкость Точка во времени; |
| tr-TR | Turkish (Turkey) | Siklik sitrülline peptid Ab.IgG: Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | 环瓜氨酸肽 抗体.IgG: Synonyms: Ab.IgG; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=63217-4
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