63298-4

Nucleosome Ab [Presence] in Body fluid by Immunoassay

Active

Part Descriptions

LP31804-5 Nucleosome
The nucleosome is the structural unit of chromatin and consists of a segment of dsDNA coiled around a histone core. Anti-chromatin autoantibodies, such as those found in patients with systemic lupus erythematosus (SLE) fall in to two categories: those directed against individual components of chromatin, such as DNA and histone, and those directed against the intact nucleosome. Traditionally anti-dsDNA antibodies have been among the ones used for diagnosis and monitoring of SLE, however, studies have shown that for some patients, the nucleosome is the primary antigen in SLE, and anti-nucleosome antibodies may provide a better reflection of disease activity. A subset of patients who are positive for anti-nucleosome antibodies but negative for anti-dsDNA antibodies may have a milder course of SLE that does not involve the kidneys. PMID: 25193804 Source: Regenstrief LOINC, PMID: 25193804

LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Nucleosome Ab:PrThr:Pt:Body fld:Ord:IA
Long Common Name: Nucleosome Ab [Presence] in Body fluid by Immunoassay
Short Name: Nucleosome Ab Fld Ql IA
Display Name: Nucleosome Ab IA Ql (Body fld)
Consumer Name Alpha Get Info: Nucleosome antibody, Body fluid

Part Model Get Info

Component
Nucleosome Ab
LP39217-2
- Analyte
  Nucleosome Ab
  LP39217-2
  - Component Numerator
    Nucleosome Ab
    LP39217-2
    - Component Numerator Core
      Nucleosome
      LP31804-5
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Body fld
LP7238-1
- System Core
  Body fld
  LP7238-1
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IA
LP217197-5

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.36
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Nukleozom Ab:Přítomnost nebo práh:Časový bod:Tělní tekutina:Ordinální:Imunoanalýza
el-GR	Greek (Greece)	Νουκλεόσωμα Αντίσωμα:PrThr:Pt:Σωματικό υγρό:Ord:IA Synonyms: IA Ord PrThr Pt SERO Αντίσωμα Νουκλεόσωμα Σωματικό υγρό
es-ES	Spanish (Spain)	Nucleosoma Anticuerpos:PrThr:Punto temporal:Fluido corporal:Ord:IA
es-MX	Spanish (Mexico)	Ab nucleosoma:Presencia o umbral:Punto temporal:Fluído corporal:Ordinal:Inmunoensayo
et-EE	Estonian (Estonia)	Nukleosoom antikehad:PrThr:Pt:Fx:Ord:IA Synonyms: Järgarvuline Juhuslik Kehavedelik
fr-CA	French (Canada)	Nucléosome, Ac:Présence-Seuil:Temps ponctuel:Liquide biologique:Ordinal:IA
fr-FR	French (France)	Nucléosomes Ac:Présence/Seuil:Ponctuel:Liquide biologique:Qualitatif:Immunoanalyse
fr-BE	French (Belgium)	Nucléosome Ac:PrThr:Temps ponctuel:Liquide biologique:Ordinal:IA Synonyms: Anticorps
it-IT	Italian (Italy)	Nucleosoma Ab:PrThr:Pt:Liquido corporeo:Ord:IA Synonyms: anticorpo Immunoassay Liquido corporeo Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	nucleosoom As:aanwezigheid:moment:lichaamsvocht:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Nukleosom Ab:granica wykrywalności:punkt w czasie:płyn ustrojowy:uporządkowany:metoda immunologiczna Synonyms: Przeciwciała do nukleosomów
ru-RU	Russian (Russian Federation)	Нуклеосома Ат:PrThr:ТчкВрм:Тело ждк:Пор:IA Synonyms: Антитело Порядковый Тела жидкость Точка во времени;Момент
tr-TR	Turkish (Turkey)	Nükleozom Ab:MevcEşik:Zmlı:Vücut sv:Srl:İA Synonyms: Ak İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	核小体抗体:存在情况或阈值:时间点:体液:序数型:免疫测定法 Synonyms: Ab;自身抗体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间核小体 Ab 核粒核粒 Ab 核粒抗体物体血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.