Version 2.77

Part Descriptions

LP30843-4   Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein. Source: Regenstrief LOINC

LP37039-2   Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor. Source: ARUP Laboratories

LP37039-2   Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system. Source: Regenstrief LOINC

Fully-Specified Name

Component
Amphiphysin Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IA

Additional Names

Short Name
Amphiphysin Ab CSF Ql IA
Display Name
Amphiphysin Ab IA Ql (CSF)
Consumer Name Alpha Get Info
Amphiphysin antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG24036-2 Amphiphysin Ab|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Anfifisina Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:IA
es-MX Spanish (Mexico) Amphiphysin Ab:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunoensayo
et-EE Estonian (Estonia) Amfifüsiin antikehad:PrThr:Pt:CSF:Ord:IA
Synonyms: Järgarvuline Juhuslik Liikvor
fr-CA French (Canada) Amphiphysine , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:IA
fr-FR French (France) Amphiphysine anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoanalyse
fr-BE French (Belgium) Amphiphysine Ac:PrThr:Temps ponctuel:LCR:Ordinal:IA
Synonyms: Anticorps
it-IT Italian (Italy) Amfifisina Ab:PrThr:Pt:LCS:Ord:IA
Synonyms: anticorpo Immunoassay Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) amfifysine As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
ru-RU Russian (Russian Federation) Амфифизин Ат:PrThr:ТчкВрм:ЦСЖ:Пор:IA
Synonyms: Антитело Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Amfifizin Ab:MevcEşik:Zmlı:BOS:Srl:İA
Synonyms: Ak İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 双载蛋白 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫测定法
Synonyms: Ab;自身抗体 Amphiphysin Ab CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 两亲蛋白;两性蛋白;Amphiphysin（一种位于神经元突触前膜的 128kD 蛋白）;神经元突触囊泡 Amphiphysin;两性蛋白(僵直人综合征伴乳腺癌128kDa 自身抗原);amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63383-4