63420-4

Gliadin peptide+tissue transglutaminase IgA+IgG Ab [Presence] in Serum by Immunoassay

Active

Part Description

LP113725-8 Gliadin peptide+tissue transglutaminase
The presence of antibodies to gliadin peptide and tissue transglutaminase can be used in conjunction with clinical findings and other lab tests to aid in the diagnosis of IgA sufficient and IgA deficient celiac disease.

Antibodies to deamidated gliadin peptide and tissue transglutaminase are specific to Celiac Disease while antibodies to gliadin are present in patients with and without gastrointestinal manifestations and are serological evidence of gluten sensitivity.

The screening starts with testing for IgA and IgG antibodies to deamidated gliadin peptide (DGP) and tissue transglutaminase (tTG) that allows for simultaneous detection for all four types of antibodies in one test (tTG/DGP screen). This step will aid in the diagnosis of gluten-sensitive enteropathies including celiac disease. Antibodies to DGP and tTG are highly specific and sensitive for those conditions When the result is positive, testing stops. When result is negative, testing will reflex to a second step. Source: LOINC partner 1

Fully-Specified Name

Component: Gliadin peptide+Tissue transglutaminase Ab.IgA+IgG
Property: PrThr
Time: Pt
System: Ser
Scale: Ord
Method: IA

Additional Names

Short Name: Gliadin peptide+tTG IgA+IgG Ser Ql IA
Display Name: Gliadin peptide+tissue transglutaminase IgA+IgG IA Ql (S)
Consumer Name Alpha Get Info: Gliadin peptide+Tissue transglutaminase IgA+IgG, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.36
Last Updated: Version 2.73
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 2044

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Gliadina+transglutaminasa tisular IgA+IgG:PrThr:Punto temporal:Suero:Ord:IA
es-MX	Spanish (Mexico)	Péptido de gliadina + transglutaminasa tisular Ab.IgA + IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
et-EE	Estonian (Estonia)	Gliadiin + koe transglutaminaas Antikehad.IgA+IgG:PrThr:Pt:S:Ord:IA Synonyms: Immuunglobuliin A Immuunglobuliin G Järgarvuline Juhuslik Seerum
fr-CA	French (Canada)	Toxine 1 du syndrôme du choc toxique de Staphylococcus aureus , IgA+IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FR	French (France)	Gliadine peptide+transglutaminase tissulaire anticorps IgA+IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-BE	French (Belgium)	Gliadine peptidique+Transglutaminase de tissu Anticorps. IgA+IgG:PrThr:Temps ponctuel:Sérum:Ordinal:IA Synonyms: Anticorps
it-IT	Italian (Italy)	Peptide della gliadina+Transglutaminasi tissutale Ab.IgA+IgG:PrThr:Pt:Siero:Ord:IA Synonyms: anticorpi anti-IgA anticorpi anti-IgA+IgG anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	gliadinepeptide + tissue transglutaminase As.IgA + IgG:aanwezigheid:moment:serum:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Peptyd gliadyny+transglutaminaza tkankowa Ab.IgA +IgG:granica wykrywalności:punkt w czasie:surowica:półilościowy:metoda immunologiczna Synonyms: IgG Immunoglobulina A Peptyd gliadyny i transglutaminaza tkankowa Przeciwciała do peptydu gliadyny i transglutaminazy tkankowej Przeciwciała IgA i IgG do peptydu gliadyny i transglutaminazy tkankowej
ru-RU	Russian (Russian Federation)	Глиадин пептид+тканевая трансглутаминаза Ат.IgA+IgG:PrThr:ТчкВрм:Сыв:Пор:IA Synonyms: Антитело Пептиды глиадина Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Gliadin peptid+doku transglutaminaz Ab.IgA+IgG:MevcEşik:Zmlı:Ser:Srl:İA Synonyms: Ak Ak.IgA+IgG IgA İmmünölçüm, immünoassay Mevcut
uk-UA	Ukrainian (Ukraine)	Гліадін пептид+Тканинна трансглутаміназа Антитіла.IgA+IgG:Наявність або Поріг:МоментЧасу:Сироватка:Порядково:Імуноаналіз Synonyms: ABS; Aby; Agf98; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Celiac; Celiac disease; Deamidated gliadin peptide; Deaminated gliadin; DGP; EIA; ELFA; ELISA; Enzyme immunoassay; F98; Fibrin stabilizing factor; Gastro; Gastroenterology; GI; Gliadin peptide+tTG; Gliadine; IAA; Immune globulin A; Immune globulin G; Immunoglobulin A; Immunoglobulin G; MEIA; Ordinal; Pept; Point in time; PR; Protein-glutamine gamma glutamyltransferase; QL; Qual; Qualitative; Random; Screen; Serology; Serum; SR; SUDS; TG2; tTG; tTG antibodies; tTg/DGP
zh-CN	Chinese (China)	麦醇溶蛋白肽+组织谷氨酰胺转移酶抗体.IgA+IgG:存在情况或阈值:时间点:血清:序数型:免疫测定法 Synonyms: Ab.IgA;IgA;抗体 IgA Ab.IgA+IgG;IgA+IgG;抗体 IgA+抗体 IgG Ab;自身抗体 tTG;第十三因子;纤维蛋白稳定因子;纤维蛋白稳定因子（Fibrin stabilizing factor）;组织谷氨酰胺转移酶（Tissue transglutaminase，tTG）;组织转谷氨酰胺酶;蛋白质-谷氨酰胺 gamma 谷氨酰胺转移酶;蛋白质-谷氨酰胺 gamma 谷氨酰胺转移酶（Protein-glutamine gamma glutamyltransferase）;蛋白质-谷氨酰胺 gamma 转谷氨酰胺酶;血纤维稳定因子;血纤维蛋白稳定因子依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 A 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间组织谷氨酰胺转移酶 Ab 组织谷氨酰胺转移酶 Ab.IgA 组织谷氨酰胺转移酶 IgA 组织转谷氨酰胺酶 Ab 组织转谷氨酰胺酶 Ab.IgA 组织转谷氨酰胺酶抗体组织转谷氨酰胺酶抗体.IgA 缩氨酸血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类醇溶朊;醇溶蛋白;麦胶蛋白;麸朊;麸蛋白醇溶朊肽;醇溶蛋白肽;麦胶蛋白肽;麸朊肽;麸蛋白肽醇溶朊肽;醇溶蛋白肽;麦胶蛋白肽;麸朊肽;麸蛋白肽;麦醇溶蛋白肽+组织转谷氨酰胺酶醇溶蛋白IgG 麦胶蛋白IgG 麸朊IgG 麸蛋白IgG

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63420-4

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.