63532-6
Centromere protein B Ab [Presence] in Body fluid by Immunoassay
Active
Part Descriptions
LP71684-2 Centromere protein B Ab
Major centromere autoantigen B, also known as centromere protein B or CENP-B, is encoded by the CENPB gene located on chromosome 20p13. CENP-B interacts with chromosomal centromeric heterochromatin and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. [UniProt: P07199] CENP-B plays a direct role in stablizing CENP-C, which is a kinetochore assembly nucleator, and recruiting CENP-A, which marks and maintains centromere position. Chromosomes that have centromeres without bound CENP-B, including the human Y chromosome, are more likely to missegregate at much higher rates than chromosomes with CENP-B containing centromeres. PMID: 25942623 Autoantibodies to both CENP-A and CENP-B are markers for scleroderma and other rheumatic diseases. PMID: 17210244
Source: Regenstrief LOINC,
UniProt: P07199
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Centromere protein B Ab:
PrThr: Pt: Body fld: Ord: IA - Long Common Name
- Centromere protein B Ab [Presence] in Body fluid by Immunoassay
- Short Name
- Centromere B Ab Fld Ql IA
- Display Name
- Centromere protein B Ab IA Ql (Body fld)
- Consumer Name Alpha Get Info
- Centromere Protein B antibody, Body fluid
Part Model Get Info
- Component
- Centromere protein B Ab
LP71684-2
- Analyte
- Centromere protein B Ab
LP71684-2
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- PrThr
LP217195-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Body fld
LP7238-1
- System Core
- Body fld
LP7238-1
- Super System
- NULL
- Scale
- Ord
LP7751-3
- Method
- IA
LP217197-5
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Centromera protein B Ab: |
| el-GR | Greek (Greece) | Πρωτεΐνη κεντρομερούς Β Αντίσωμα: Synonyms: B IA Ord PrThr Pt SERO Αντίσωμα Κεντρομερίδιο Πρωτεΐνη Πρωτεΐνη κεντρομερούς Β Σωματικό υγρό |
| es-ES | Spanish (Spain) | Proteína B del centrómero Anticuerpos: |
| es-MX | Spanish (Mexico) | Centrómero de proteína B Ab: |
| et-EE | Estonian (Estonia) | Tsentromeer B vastased antikehad: Synonyms: Järgarvuline Juhuslik Kehavedelik |
| fr-CA | French (Canada) | Centromère protéine B, Ac: |
| fr-FR | French (France) | Centromère protéine B Ac: |
| fr-BE | French (Belgium) | Centromère. Protéine B Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Centromero, proteina B Ab: Synonyms: anticorpo Immunoassay Liquido corporeo Presenza o Soglia Proteina B del centromero Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | centromeereiwit B As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Białko centromerowe B Ab: Synonyms: CENP-B Przeciwciała do antygenu B Przeciwciała do centromerowego białka F |
| ru-RU | Russian (Russian Federation) | Центромерный протеин B Ат: Synonyms: Антитело Белок Порядковый Тела жидкость Точка во времени; |
| tr-TR | Turkish (Turkey) | Sentromer protein B Ab: Synonyms: Ak İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 着丝点蛋白 B 抗体: Synonyms: Ab; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://