63533-4
Centromere protein B Ab [Presence] in Cerebral spinal fluid by Immunoassay
Active
Part Description
LP71684-2 Centromere protein B Ab
Major centromere autoantigen B, also known as centromere protein B or CENP-B, is encoded by the CENPB gene located on chromosome 20p13. CENP-B interacts with chromosomal centromeric heterochromatin and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. [UniProt: P07199] CENP-B plays a direct role in stablizing CENP-C, which is a kinetochore assembly nucleator, and recruiting CENP-A, which marks and maintains centromere position. Chromosomes that have centromeres without bound CENP-B, including the human Y chromosome, are more likely to missegregate at much higher rates than chromosomes with CENP-B containing centromeres. PMID: 25942623 Autoantibodies to both CENP-A and CENP-B are markers for scleroderma and other rheumatic diseases. PMID: 17210244
Source: Regenstrief LOINC, UniProt: P07199
Fully-Specified Name
- Component
- Centromere protein B Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- Centromere B Ab CSF Ql IA
- Display Name
- Centromere protein B Ab IA Ql (CSF)
- Consumer Name Alpha Get Info
- Centromere Protein B antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG29561-4 | Centromere protein B Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Proteína B del centrómero Anticuerpos: |
| es-MX | Spanish (Mexico) | Centrómero de proteína B Ab: |
| et-EE | Estonian (Estonia) | Tsentromeer B vastased antikehad: Synonyms: Järgarvuline Juhuslik Liikvor |
| fr-CA | French (Canada) | Centromère protéine B , Ac: |
| fr-FR | French (France) | Centromère protéine B anticorps: |
| fr-BE | French (Belgium) | Centromère. Protéine B Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Centromero, proteina B Ab: Synonyms: anticorpo Immunoassay Liquido cerebrospinale Presenza o Soglia Proteina B del centromero Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | centromeereiwit B As: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | Центромерный протеин B Ат: Synonyms: Антитело Белок Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Sentromer protein B Ab: Synonyms: Ak İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 着丝点蛋白 B 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright