63568-0
Neutrophil cytoplasmic Ab pattern [Interpretation] in Cerebral spinal fluid by Immunofluorescence
Active
Part Description
LP16728-5 Neutrophil cytoplasmic
Neutrophil cytoplasmic antibodies are autoantibodies that bind to the granulocytes of neutrophils. These antibodies were first identified in patients with Wegener's granulomatosis (WG) who also had systemic vasculitis and necrotizing crescentic glomerulonephritis. When viewed under a fluorescent microscope, a typical cytoplasmic fluorescent pattern is visible. These ANCA are called cytoplasmic ANCA (c-ANCA) and the antigen they target is proteinase 3 (PR3) which is part of the azurophilic granules of neutrophils. The perinuclear ANCA (p-ANCA) targets the antigen myeloperoxidase (MPO) and is associated with idiopathic forms of systemic vasculitis and glomerulonephritis. A third ANCA antibody is the atypical ANCA (a-ANCA). The presence of a-ANCA has been found in patients with inflammatory bowel diseases including ulcerative colitis (UC) and Crohn's disease (CD), autoimmune-mediated liver diseases, rheumatoid arthritis RA, and systemic lupus erythematosus (SLE). PMID: 27366026
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neutrophil cytoplasmic Ab pattern
- Property
- Imp
- Time
- Pt
- System
- CSF
- Scale
- Nom
- Method
- IF
Additional Names
- Short Name
- ANCA Ab pattern CSF IF-Imp
- Display Name
- Neutrophil cytoplasmic Ab pattern IF (CSF) [Interp]
- Consumer Name Alpha Get Info
- Neutrophil cytoplasmic Ab pattern, Spinal fluid
Example Answer List: LL1421-8
Source: Regenstrief LOINCAnswer | Code | Score | Answer ID |
---|---|---|---|
Diffuse granular cytoplasmic | LA15817-2 | ||
Perinuclear | LA15818-0 | ||
Fine speckled | LA15819-8 | ||
Linear | LA15815-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.36
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Citoplasma de neutrófilo Patrón de anticuerpos: |
es-MX | Spanish (Mexico) | Patrón de Ab citoplasmático de neutrófilos: |
fr-CA | French (Canada) | Neutrophile cytoplasmique, Patron des Ac: |
fr-FR | French (France) | Cytoplasme des polynucléaires neutrophiles anticorps aspect: |
fr-BE | French (Belgium) | Neutrophile cytoplasmique Anticorps.Profil des Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Neutrofilo citoplasmico profilo Ab: Synonyms: anticorpo Immunofluorescenza (IF) Impressione/interpretazione di studio Liquido cerebrospinale profilo anticorpo Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | neutrofiel cytoplasmatisch As-patroon: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Нейтрофилов цитоплазматический Ат паттерн: Synonyms: Антитело Впечатление/интерпретация исследования Иммунофлюоресценция (ИФ) Номинальный; |
tr-TR | Turkish (Turkey) | Nötrofil sitoplazmik Ab yapısı: Synonyms: Ak Ak yapısı İmmünflorerans |
zh-CN | Chinese (China) | 嗜中性粒细胞细胞浆 抗体模式: Synonyms: Ab; |
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LOINC Copyright
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