Version 2.78

Term Description

In this test panel both CD3+ and CD4+ are required to recognize CD4 T cells (helper cells), and both CD3+ and CD8+ to recognize CD8 T cells (suppressor cells). The measurement of Helper T-cell levels has been used to establish decision points for initiating P. jiroveci prophylaxis, antiviral therapy and to monitor the efficacy of treatment. The Public Health Service (PHS) has recommended that Helper T-cell levels be monitored every three to six months in all HIV-infected persons.

During HIV infection, antiviral therapy is often initiated when the absolute CD4 T cell count drops below 500 cells/µL. When the absolute CD4 T cell count drops below 200 cells/µL, therapeutic prophylaxis against PCP and other opportunistic infections may be initiated. When the absolute CD4 T cell count drops below 100 cells/µL, prophylaxis against Mycobacterium avium complex is recommended. (from ARUP, modified)
Source: Regenstrief LOINC

Part Descriptions

LP14443-3   CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
65759-3 T-cell subsets CD4 and CD8 panel - Blood
Indent26474-7 Lymphocytes [#/volume] in Blood C 10*3/uL
Indent27071-0 CD45 (Lymphs) cells [#/volume] in Blood C /uL
Indent8122-4 CD3 cells [#/volume] in Blood R /uL
Indent8124-0 CD3 cells/100 cells in Blood O %
Indent24467-3 CD3+CD4+ (T4 helper) cells [#/volume] in Blood R /uL
Indent8123-2 CD3+CD4+ (T4 helper) cells/100 cells in Blood O %
Indent14135-8 CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood R /uL
Indent8101-8 CD3+CD8+ (T8 suppressor) cells/100 cells in Blood O %
Indent54218-3 CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood O %

Fully-Specified Name

Component
T-cell subsets CD4 & CD8 panel
Property
-
Time
Pt
System
Bld
Scale
-
Method

Additional Names

Short Name
T-cell subsets CD4+CD8 pnl Bld
Display Name
T-cell subsets CD4 and CD8 panel (Bld)
Consumer Name Alpha Get Info
T-cell Subsets CD4 and CD8 Panel, Blood

Basic Attributes

Class
PANEL.CELLMARK
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.73
Order vs. Observation
Order
Common Test Rank Get Info
2356
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Perfil de subpoblaciones celulares T CD4 y CD8:Propiedades mixtas (sólo paneles):Punto temporal:Sangre:-:
es-MX Spanish (Mexico) Panel de subconjuntos de células T CD4 y CD8:-:Punto temporal:Sangre:-:
fr-FR French (France) Sous-populations lymphocytaires CD4 et Cd8 panel:-:Ponctuel:Sang:-:
it-IT Italian (Italy) Subsets CD4 & CD8 di linfociti T, panel:-:Pt:Sangue:-:
Synonyms: Linfocita T Modelli di superficie cellulare Panel subsets CD4 e CD8 di linfociti T Punto nel tempo (episodio) Sangue Set di prescrizione per marcatore cellulare
nl-NL Dutch (Netherlands) T-cell subsets CD4 & CD8 panel:-:moment:bloed:-:
ru-RU Russian (Russian Federation) T-клетки подмножества CD4 & CD8 панель:-:ТчкВрм:Кр:-:
Synonyms: Кровь Точка во времени;Момент
zh-CN Chinese (China) T-细胞亚群 CD4 与 CD8 组套:-:时间点:全血:-:
Synonyms: L3T4 Leu2 Leu-2 Leu3 Leu-3 T 细胞;UCHL-1 T4 T-4 T8 T-8 Tsuppressor T-细胞亚群（子群、子集） CD4 与 CD8 组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） W3/25 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.细胞标志物;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）类.细胞标志物;实验室医嘱组类.细胞标志物;细胞标志物医嘱组;细胞标志物医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 发现于辅助 T-细胞；微弱表达于单核细胞。与相关。一些成熟 T-细胞肿瘤，包括大多数情况下的 T-细胞慢性淋巴细胞白血病/前淋巴细胞白血病、外周 T-细胞淋巴瘤、成人 T-细胞白血病/淋巴瘤以及 Sézary 综合征（T 细胞红皮病）/蕈样肉芽肿（mycosis fungoides）。 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 抑制性 T 细胞 抑制性 T-细胞 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 细胞标志物 血;血液 诱导 T 细胞 诱导性 T 细胞 辅助 T 细胞 辅助诱导 T 细胞 辅助诱导物 T 细胞

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=65759-3
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/65759-3