65759-3
T-cell subsets CD4 and CD8 panel - Blood
Active
26474-7 Lymphocytes [#/volume] in Blood
Part Descriptions
LP14540-6 Lymphocytes
White blood cells formed in lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin whereas the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T cells (transit through the thymus), B cells or natural killer cells (NK).
Source: National Library of Medicine, MeSH 2006
LP14540-6 Lymphocytes
A lymphocyte is a type of white blood cell in the vertebrate immune system.
A lymphocyte count is usually part of a peripheral complete blood cell count and is expressed as percentage of lymphocytes to total white blood cells counted. A general increase in the number of lymphocytes is known as lymphocytosis whereas a decrease is lymphocytopenia.
An increase in lymphocyte concentration is usually a sign of a viral infection (in some rare case, leukemias are found through an abnormally raised lymphocyte count in an otherwise normal person).
A low normal to low absolute lymphocyte concentration is associated with increased rates of infection after surgery or trauma.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Lymphocytes (Wikipedia)
Condition for Inclusion
Need one of a) an abs lymphocyte count from the hematology auto analyzer or b) an abs CD45 count trom flow cytometer to obtain an absolute lymphocyte count
Observation Required in Panel
Conditional
Fully-Specified Name
- Component
- Lymphocytes
- Property
- NCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- Lymphocytes # Bld
- Display Name
- Lymphocytes (Bld) [#/Vol]
- Consumer Name Alpha Get Info
- Lymphocytes, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 112
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 69742-5 | CBC W Differential panel, method unspecified - Blood |
| 57782-5 | CBC W Ordered Manual Differential panel - Blood |
| 57022-6 | CBC W Reflex Manual Differential panel - Blood |
| 24361-8 | Deprecated Hemogram, platelets & Differential panel in Blood |
| 34527-2 | Deprecated Hemogram, Platelets, Differential & Reticulocyte panel in Blood |
| 69738-3 | Differential panel, method unspecified - Blood |
| 24359-2 | Hemogram without Platelets and with Manual Differential panel - Blood |
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 48808-0 | Leukogram panel - Blood |
| 24318-8 | Manual Differential panel - Blood |
| 55429-5 | Short blood count panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32863-9 | Lymphocytes| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Lymphozyten abs. |
| de-DE | German (Germany) | Lymphozyten: |
| es-AR | Spanish (Argentina) | linfocitos: |
| es-ES | Spanish (Spain) | Linfocitos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Linfocitos: |
| et-EE | Estonian (Estonia) | Lümfotsüüdid: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Lymphocytes: |
| fr-FR | French (France) | Lymphocytes totaux: |
| fr-BE | French (Belgium) | Lymphocytes: |
| it-IT | Italian (Italy) | Linfociti: Synonyms: Concentrazione Numerica Ematologia (coagulazione) conta differenziale Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 림프구: |
| nl-NL | Dutch (Netherlands) | lymfocyten: |
| pl-PL | Polish (Poland) | Limfocyty: Synonyms: koncentracja Limfocyty |
| pt-BR | Portuguese (Brazil) | Linfócitos: Synonyms: Lymphs; |
| ru-RU | Russian (Russian Federation) | Лимфоциты: Synonyms: Количественный Количество в объеме Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Lenfositler: |
| uk-UA | Ukrainian (Ukraine) | Лімфоцити: Synonyms: #; |
| zh-CN | Chinese (China) | 淋巴细胞: Synonyms: 单位体积内的数量或计数; |
Example Units
| Unit | Source |
|---|---|
| 10*3/uL | Example UCUM Units |
| k/cumm | REGENSTRIEF |
27071-0 CD45 (Lymphs) cells [#/volume] in Blood
Part Descriptions
LP17732-6 Cells.CD45
CD45 marker identifies lymphocytes in flow cytometry. CD45 markers, along with special beads are used to determine the absolute lymphocyte count by some laboratories. (Other labs use the total lymphocyte count from the CBC).
Source: Regenstrief Help
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | CD45 markers along with special beads are used to determine the absolute lymphocyte count by some laboratories. (Others use the total lymphocyte count from the CBC.) Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Condition for Inclusion
Need one of a) an abs lymphocyte count from the hematology auto analyzer or b) an abs CD45 count trom flow cytometer to obtain an absolute lymphocyte count
Observation Required in Panel
Conditional
Fully-Specified Name
- Component
- Cells.CD45
- Property
- NCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD45 Cells # Bld
- Display Name
- CD45 (Lymphs) cells (Bld) [#/Vol]
- Consumer Name Alpha Get Info
- CD45 (Lymphs) Cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 3585
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 100994-3 | B-cell CD19 and CD20 subsets panel - Blood by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 98073-0 | Natural killer and natural killer T cell subsets panel - Blood |
| 53759-7 | Natural killer cell panel - Blood by Flow cytometry (FC) |
| 65758-5 | T-cell helper (CD4) subset panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CD45 |
| de-DE | German (Germany) | Zellen.CD45: |
| es-AR | Spanish (Argentina) | células.CD45: |
| es-MX | Spanish (Mexico) | Cells.CD45: |
| es-ES | Spanish (Spain) | Células CD45+: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Rakud.CD45: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD45: |
| fr-FR | French (France) | CD45: |
| fr-BE | French (Belgium) | Cellules.CD45: |
| it-IT | Italian (Italy) | Cellule.CD45: Synonyms: Cellule CD45 Concentrazione Numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD45: |
| nl-NL | Dutch (Netherlands) | cellen.CD45: |
| pl-PL | Polish (Poland) | Komórki.CD45: Synonyms: CD45 Komórki CD45 koncentracja |
| pt-BR | Portuguese (Brazil) | Células.CD45: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD45: Synonyms: CD45 (Лимфатические) клетки Количественный Количество в объеме Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD45: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD45: Synonyms: #; |
| zh-CN | Chinese (China) | 细胞.CD45: Synonyms: B220; |
Example Units
| Unit | Source |
|---|---|
| /uL | Example UCUM Units |
| k/cumm | REGENSTRIEF |
8122-4 CD3 cells [#/volume] in Blood
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | T-cells of all kind Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Required
Fully-Specified Name
- Component
- Cells.CD3
- Property
- NCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3 Cells # Bld
- Display Name
- CD3 cells (Bld) [#/Vol]
- Consumer Name Alpha Get Info
- CD3 cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 749
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 95184-8 | Cytomegalovirus T-cell immunodeficiency panel - Blood by Flow cytometry (FC) |
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: T-Zellen (3+) abs. |
| de-DE | German (Germany) | Zellen.CD3: |
| es-AR | Spanish (Argentina) | células.CD3: |
| es-ES | Spanish (Spain) | Células CD3: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cells.CD3: |
| et-EE | Estonian (Estonia) | Rakud.CD3: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3: |
| fr-FR | French (France) | CD3: |
| fr-BE | French (Belgium) | Cellules.CD3: |
| it-IT | Italian (Italy) | Cellule.CD3: Synonyms: Cellule CD3 Concentrazione Numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD3: |
| nl-NL | Dutch (Netherlands) | cellen.CD3: |
| pt-BR | Portuguese (Brazil) | Células.CD3: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3: Synonyms: Количественный Количество в объеме Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3: Synonyms: #; |
| zh-CN | Chinese (China) | 细胞.CD3: Synonyms: CD3细胞 Leu4; |
Example Units
| Unit | Source |
|---|---|
| /uL | Example UCUM Units |
| 10^9/L | eCHN |
8124-0 CD3 cells/100 cells in Blood
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | T-cells of all kind Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Optional
Fully-Specified Name
- Component
- Cells.CD3/100 cells
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3 Cells NFr Bld
- Display Name
- CD3 cells/100 cells (Bld)
- Consumer Name Alpha Get Info
- CD3 cells per 100 cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 756
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 45268-0 | Immunodeficiency panel - Blood by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: T-Lymphozyten [Lympho] |
| de-DE | German (Germany) | Zellen.CD3/100 Zellen: |
| es-AR | Spanish (Argentina) | células.CD3/100 células: |
| es-ES | Spanish (Spain) | Células CD3/100 células: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cells.CD3 / 100 células: |
| et-EE | Estonian (Estonia) | Rakud.CD3/100 raku kohta: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3/100 cellules: |
| fr-FR | French (France) | CD3/100 cellules: |
| fr-BE | French (Belgium) | Cellules.CD3/100 cellules: |
| it-IT | Italian (Italy) | Cellule.CD3/100 cellule: Synonyms: Cellule CD3 Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD3/100 세포: |
| nl-NL | Dutch (Netherlands) | cellen.CD3/100 cellen: |
| pt-BR | Portuguese (Brazil) | Células.CD3/100 células: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3/100 клеток: Synonyms: Количественный Количество отношение Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3/100 hücre: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3/100 клітин: Synonyms: Blood; |
| zh-CN | Chinese (China) | 细胞.CD3/100 个细胞: Synonyms: CD3细胞 Leu4; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |
24467-3 CD3+CD4+ (T4 helper) cells [#/volume] in Blood
Part Descriptions
LP14441-7 Cells.CD3+CD4+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP14441-7 Cells.CD3+CD4+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc).
Source: Regenstrief Help
LP14443-3 CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | CD3 as well as CD4 are required to identify CD4 T-cells (CD4 helper cell). Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Required
Fully-Specified Name
- Component
- Cells.CD3+CD4+
- Property
- NCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3+CD4+ Cells # Bld
- Display Name
- CD3+CD4+ (T4 helper) cells (Bld) [#/Vol]
- Consumer Name Alpha Get Info
- CD3+CD4+ (T4 Helper) Cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0o
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 621
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65758-5 | T-cell helper (CD4) subset panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Helfer-T-Z.(4+) abs. |
| de-DE | German (Germany) | Zellen.CD3+CD4+: |
| es-AR | Spanish (Argentina) | células.CD3+CD4+: |
| es-ES | Spanish (Spain) | Células CD3+CD4+: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Células CD3 + CD4 +: |
| et-EE | Estonian (Estonia) | Rakud.CD3+CD4+: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3+CD4+: |
| fr-FR | French (France) | CD3+CD4+: |
| fr-BE | French (Belgium) | Cellules.CD3+CD4+: |
| it-IT | Italian (Italy) | Cellule.CD3+CD4+: Synonyms: Cellule CD3 Cellule CD3+CD4+ Cellule CD3-CD4+ Concentrazione Numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD3+CD4+: |
| nl-NL | Dutch (Netherlands) | cellen.CD3+CD4+: |
| pt-BR | Portuguese (Brazil) | Células.CD3+CD4+: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3+CD4+: Synonyms: CD3+CD4+ (T4 хэлперы) клетки Количественный Количество в объеме Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3+CD4+: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3+CD4+: Synonyms: #; |
| zh-CN | Chinese (China) | 细胞.CD3+CD4+: Synonyms: CD3+CD4+细胞 CD3-CD4+细胞 CD3细胞 L3T4 Leu3 Leu-3 Leu4; |
Example Units
| Unit | Source |
|---|---|
| /uL | Example UCUM Units |
| 10^9/L | eCHN |
8123-2 CD3+CD4+ (T4 helper) cells/100 cells in Blood
Part Descriptions
LP14441-7 Cells.CD3+CD4+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP14441-7 Cells.CD3+CD4+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc).
Source: Regenstrief Help
LP14443-3 CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | CD3 as well as CD4 are required to identify CD4 T-cells (CD4 helper cell). Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Optional
Fully-Specified Name
- Component
- Cells.CD3+CD4+/100 cells
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3+CD4+ Cells NFr Bld
- Display Name
- CD3+CD4+ (T4 helper) cells/100 cells (Bld)
- Consumer Name Alpha Get Info
- CD3+CD4+ (T4 Helper) Cells per 100 cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 610
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 45268-0 | Immunodeficiency panel - Blood by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65758-5 | T-cell helper (CD4) subset panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Helferzellen [Lympho] |
| de-DE | German (Germany) | Zellen.CD3+CD4+/100 Zellen: |
| es-AR | Spanish (Argentina) | células.CD3+CD4+/100 células: |
| es-ES | Spanish (Spain) | Células CD3+CD4+/100 células: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cells.CD3 + CD4 + / 100 células: |
| et-EE | Estonian (Estonia) | Rakud.CD3+CD4+/100 raku kohta: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3+CD4+/100 cellules: |
| fr-FR | French (France) | CD3+CD4+/100 cellules: |
| fr-BE | French (Belgium) | Cellules.CD3+CD4+/100 cellules: |
| it-IT | Italian (Italy) | Cellule.CD3+CD4+/100 cellule: Synonyms: Cellule CD3 Cellule CD3+CD4+ Cellule CD3-CD4+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD3+CD4+/100 세포: |
| nl-NL | Dutch (Netherlands) | cellen.CD3+CD4+/100 cellen: |
| pt-BR | Portuguese (Brazil) | Células.CD3+CD4+/100 células: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3+CD4+/100 клеток: Synonyms: CD3+CD4+ (T4 хэлперы) клетки Количественный Количество отношение Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3+CD4+/100 hücre: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3+CD4+/100 клітин: Synonyms: Blood; |
| zh-CN | Chinese (China) | 细胞.CD3+CD4+/100 个细胞: Synonyms: CD3+CD4+细胞 CD3-CD4+细胞 CD3细胞 L3T4 Leu3 Leu-3 Leu4; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |
14135-8 CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood
Part Descriptions
LP17728-4 Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP17728-4 Cells.CD3+CD8+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc).
Source: Regenstrief Help
LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | CD3 as well as CD4 are required to identify CD4 T-cells (CD4 helper cell). Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Required
Fully-Specified Name
- Component
- Cells.CD3+CD8+
- Property
- NCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3+CD8+ Cells # Bld
- Display Name
- CD3+CD8+ (T8 suppressor) cells (Bld) [#/Vol]
- Consumer Name Alpha Get Info
- CD3+CD8+ (T8 Suppressor) Cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Change Reason
- Changed Order_Obs from 'Observation Only' to 'Both' to fit current order use cases.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 699
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 95184-8 | Cytomegalovirus T-cell immunodeficiency panel - Blood by Flow cytometry (FC) |
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Zytotox.T-Z.(8+)abs. |
| de-DE | German (Germany) | Zellen.CD3+CD8+: Synonyms: Zytotoxische T-Lymphozyten; |
| es-AR | Spanish (Argentina) | células.CD3+CD8+: |
| es-ES | Spanish (Spain) | Células CD3+CD8+: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cells.CD3 + CD8 +: |
| et-EE | Estonian (Estonia) | Rakud.CD3+CD8+: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3+CD8+: |
| fr-FR | French (France) | CD3+CD8+: |
| fr-BE | French (Belgium) | Cellules.CD3+CD8+: |
| it-IT | Italian (Italy) | Cellule.CD3+CD8+: Synonyms: Cellule CD3 Cellule CD3+CD8+ Concentrazione Numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD3+CD8+: |
| nl-NL | Dutch (Netherlands) | cellen.CD3+CD8+: |
| pt-BR | Portuguese (Brazil) | Células.CD3+CD8+: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3+CD8+: Synonyms: CD3+CD8+ (T8 клетки-супрессоры) клетки Количественный Количество в объеме Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3+CD8+: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3+CD8+: Synonyms: #; |
| zh-CN | Chinese (China) | 细胞.CD3+CD8+: Synonyms: CD3+CD8+细胞 CD3细胞 Leu2 Leu-2 Leu4; |
Example Units
| Unit | Source |
|---|---|
| /uL | Example UCUM Units |
| 10^9/L | eCHN |
8101-8 CD3+CD8+ (T8 suppressor) cells/100 cells in Blood
Part Descriptions
LP17728-4 Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP17728-4 Cells.CD3+CD8+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc).
Source: Regenstrief Help
LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | CD3 as well as CD4 are required to identify CD4 T-cells (CD4 helper cell). Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Optional
Fully-Specified Name
- Component
- Cells.CD3+CD8+/100 cells
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3+CD8+ Cells NFr Bld
- Display Name
- CD3+CD8+ (T8 suppressor) cells/100 cells (Bld)
- Consumer Name Alpha Get Info
- CD3+CD8+ (T8 Suppressor) Cells per 100 cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 719
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 45268-0 | Immunodeficiency panel - Blood by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Suppressorzellen [Lympho] |
| de-DE | German (Germany) | Zellen.CD3+CD8+/100 Zellen: Synonyms: Zytotoxische T-Lymphozyten; |
| es-AR | Spanish (Argentina) | células.CD3+CD8+/100 células: |
| es-ES | Spanish (Spain) | Células CD3+CD8+/100 células: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cells.CD3 + CD8 + / 100 células: |
| et-EE | Estonian (Estonia) | Rakud.CD3+CD8+/100 raku kohta: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3+CD8+/100 cellules: |
| fr-FR | French (France) | CD3+CD8+/100 cellules: |
| fr-BE | French (Belgium) | Cellules.CD3+CD8+/100 cellules: |
| it-IT | Italian (Italy) | Cellule.CD3+CD8+/100 cellule: Synonyms: Cellule CD3 Cellule CD3+CD8+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 세포.CD3+CD8+/100 세포: |
| nl-NL | Dutch (Netherlands) | cellen.CD3+CD8+/100 cellen: |
| pt-BR | Portuguese (Brazil) | Células.CD3+CD8+/100 células: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3+CD8+/100 клеток: Synonyms: CD3+CD8+ (T8 клетки-супрессоры) клетки Количественный Количество отношение Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3+CD8+/100 hücre: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3+CD8+/100 клітин: Synonyms: Blood; |
| zh-CN | Chinese (China) | 细胞.CD3+CD8+/100 个细胞: Synonyms: CD3+CD8+细胞 CD3细胞 Leu2 Leu-2 Leu4; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |
54218-3 CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
Part Descriptions
LP100021-7 Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP14441-7 Cells.CD3+CD4+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively.
Source: Regenstrief Help
LP14441-7 Cells.CD3+CD4+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc).
Source: Regenstrief Help
LP14443-3 CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides
Source: Regenstrief LOINC
LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | Need CD3 as well as CD4 and CD3 as well as CD8 to accurately identify ratio of CD4 T cell to CD8 T cell. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Optional
Fully-Specified Name
- Component
- Cells.CD3+CD4+/Cells.CD3+CD8+
- Property
- NRto
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- CD3+CD4+ Cells/CD3+CD8+ Cells Bld
- Display Name
- CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells (Bld) [# ratio]
- Consumer Name Alpha Get Info
- CD3+CD4+ (T4 Helper) Cells/CD3+CD8+ (T8 Suppressor Cells) Cells, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 2.27
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 726
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 49120-9 | Immunodeficiency follow-up panel - Specimen by Flow cytometry (FC) |
| 80721-4 | Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood |
| 65759-3 | T-cell subsets CD4 and CD8 panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CD4/CD8-Ratio |
| de-DE | German (Germany) | Zellen.CD3+CD4+/Zellen.CD3+CD8+: |
| es-ES | Spanish (Spain) | Células CD3+CD4+/Células CD3+CD8+: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Cells.CD3 + CD4 + / Cells.CD3 + CD8 +: |
| et-EE | Estonian (Estonia) | Rakud.CD3+CD4+/rakud. CD3+CD8+: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-CA | French (Canada) | Cellules.CD3+CD4+/Cellules.CD3+CD8+: |
| fr-FR | French (France) | CD3+CD4+/CD3+CD8+: |
| fr-BE | French (Belgium) | Cellules.CD3+CD4+/Cellules.CD3+CD8+: Synonyms: Rapport.numérique |
| it-IT | Italian (Italy) | Cellule.CD3+CD4+/Cellule.CD3+CD8+: Synonyms: Cellule CD3 Cellule CD3+CD4+ Cellule CD3+CD8+ Cellule CD3+CD8+ (cellule soppressore T8) Cellule CD3-CD4+ Modelli di superficie cellulare Punto nel tempo (episodio) Rapporto numerico Sangue |
| nl-NL | Dutch (Netherlands) | cellen.CD3+CD4+/cellen.CD3+CD8+: |
| pt-BR | Portuguese (Brazil) | Células.CD3+CD4+/Células CD3+CD8+: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Клетки.CD3+CD4+/Клетки.CD3+CD8+: Synonyms: CD3+CD4+ (T4 хэлперы) клетки CD3+CD8+ (T8 клетки-супрессоры) клетки Количественное отношение Количественный Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Hücreler.CD3+CD4+/Hücreler.CD3+CD8+: |
| uk-UA | Ukrainian (Ukraine) | Клітини.CD3+CD4+/Клітини.CD3+CD8+: Synonyms: Blood; |
| zh-CN | Chinese (China) | 细胞.CD3+CD4+/细胞.CD3+CD8+: Synonyms: CD3+CD4+细胞 CD3+CD8+细胞 CD3-CD4+细胞 CD3细胞 L3T4 Leu2 Leu-2 Leu3 Leu-3 Leu4; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |