Version 2.77

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ag
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
IF

Additional Names

Short Name
VZV Ag Islt Ql IF
Display Name
VZV Ag IF Ql (Isol)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) antigen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Virus Varicella zoster Antígeno:PrThr:Punto temporal:Aislado:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Virus de la varicela zóster Ag:Presencia o umbral:Punto temporal:Aislado:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Tuulerõugeviirus antigeen:PrThr:Pt:Is:Ord:IF
Synonyms: Isolaat Järgarvuline Juhuslik
fr-CA French (Canada) Virus varicelle-zona , Ag:Présence-Seuil:Temps ponctuel:Isolat:Ordinal:Immunofluorescence
fr-FR French (France) Varicelle zona virus Ag:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Virus varicelle-zona Ag:PrThr:Temps ponctuel:Isolat:Ordinal:Immunofluorescence
Synonyms: Antigène VZV
it-IT Italian (Italy) Varicella zoster, virus , Ag:PrThr:Pt:Isolato:Ord:IF
Synonyms: Immunofluorescenza (IF) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Virus della varicella zoster
nl-NL Dutch (Netherlands) varicella-zostervirus Ag:aanwezigheid:moment:isolaat:ordinaal:immunofluorescentie
Synonyms: antigeen IF Varicella zoster virus
ru-RU Russian (Russian Federation) Varicella zoster вирус Аг:PrThr:ТчкВрм:Изолят:Пор:ИФ
Synonyms: Иммунофлюоресценция (ИФ) Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) Varicella zoster virüsü Ag:MevcEşik:Zmlı:İzolat:Srl:IF
Synonyms: Antijen İmmünflorerans Mevcut
zh-CN Chinese (China) 水痘带状疱疹病毒 抗原:存在情况或阈值:时间点:分离株:序数型:免疫荧光法
Synonyms: Ag Ag IF DFA HHV-3 Ag HHV-3 抗原 HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 VZV Ag VZV 抗原 人类疱疹病毒 3 型 Ag 人类疱疹病毒 3 型抗原 人类疱疹病毒 III 型 Ag 人类疱疹病毒 III 型抗原 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗原免疫荧光检测 抗原免疫荧光测定 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ag 水痘病毒 Ag 水痘病毒抗原 直接免疫荧光分析 直接免疫荧光检测 直接免疫荧光测定

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=67812-8