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Term Description

This test refers to sequence-based genotyping of HIV in human plasma infected with the virus to identify genotypic resistance to Rilpivirine. The assay involves the isolation of HIV RNA from blood plasma and amplification of the protease and reverse transcriptase genes. The PCR product is sequenced and analyzed. Genotypic characteristics of the virus are used to predict resistance to Rilipvirine.

Part Description

LP135443-2   Rilpivirine
Rilpivirine (brand name Edurant) is a pharmaceutical drug, developed by Tibotec, for the treatment of HIV infection. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, http://en.wikipedia.org/wiki/Rilpivirine

LOINC Names Get Info

Fully-Specified Name
Rilpivirine:Susc:Pt:Isolate:Ord:Genotyping
Long Common Name
Rilpivirine [Susceptibility] by Genotype method
Short Name
Rilpivirine Islt Genotyp
Display Name
Rilpivirine Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Rilpivirine

Part Model Get Info

  • Component
    Rilpivirine
    LP135443-2
    • Analyte
      Rilpivirine
      LP135443-2
      • Component Numerator
        Rilpivirine
        LP135443-2
        • Component Numerator Core
          Rilpivirine
          LP135443-2
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Susc
    LP6870-2
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Genotyping
    LP28723-2

Example Answer List: LL1908-4

Source: LOINC partner 1
AnswerCodeScoreAnswer ID
SensitiveLA16549-0
ResistantLA6676-6
Resistance possibleLA17970-7

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.73 (MIN)
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Both
Common Test Rank Get Info
10946

Member of these Panels

LOINCLong Common Name
49660-4HIV susceptibility panel by Genotype method

Member of these Groups Get Info

LOINC GroupGroup Name
LG41382-9RilpivirineSusc|Isolate

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Rilpivirin:Citlivost (mikroorganismy):Časový bod:Izolát:Ordinální:Genotypizace
el-GRGreek (Greece)Ριλπιβιρίνη:Susc:Pt:Απομονωμένο στέλεχος:Ord:Γονοτύπηση
Synonyms: ABXBACT Ord Pt Susc Απομονωμένο στέλεχος Γονοτύπηση Ριλπιβιρίνη
es-ESSpanish (Spain)Rilpivirina:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MXSpanish (Mexico)Rilpivirina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-CAFrench (Canada)Rilpivirine:Susceptibilité:Temps ponctuel:Isolat:Ordinal:Génotypage
fr-FRFrench (France)Rilpivirine:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-ITItalian (Italy)Rilpivirina:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NLDutch (Netherlands)rilpivirine:gevoeligheid:moment:isolaat:ordinaal:genotypering
pl-PLPolish (Poland)Rylpiwiryna:wrażliwość:punkt w czasie:izolat:uporządkowany:genotypowanie
Synonyms: wrażliwość (mikroorganizmów)
ru-RURussian (Russian Federation)Рилпивирин:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TRTurkish (Turkey)Rilpivirin:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CNChinese (China)利匹韦林:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 4-[4-[4-[(E)-2-Cyanovinyl]-2,6-dimethylphenylamino]pyrimidin-2-ylamino]benzonitrile;Rilpivirine;R-278474，TMC-278;4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile;4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]a 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=68463-9