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Part Description

LP19423-0   Cytokeratin 19
Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a protein that in humans is encoded by the KRT19 gene.

Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Depending on the assays, KRT19 has been shown to be both a specific and a non-specific marker. False positivity in such KRT19 RT-PCR studies include: illegitimate transcription (expression of small amounts of KRT19 mRNA by tissues in which it has no real physiological role), haematological disorders (KRT19 induction in peripheral blood cells by cytokines and growth factors, which circulate at higher concentrations in inflammatory conditions and neutropenia), the presence of pseudogenes (two KRT19 pseudogenes, KRT19a and KRT19b, have been identified, which have significant sequence homology to KRT19 mRNA. Subsequently, attempts to detect the expression of the authentic KRT19 may result in the detection of either or both of these pseudogenes), sample contamination (introduction of contaminating epithelial cells during peripheral blood sampling for subsequent RT-PCR analysis).

Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Cytokeratin 19:MCnc:Pt:CSF:Qn:
Long Common Name
Cytokeratin 19 [Mass/volume] in Cerebrospinal Fluid
Short Name
CK 19 CSF-mCnc
Display Name
Cytokeratin 19 (CSF) [Mass/Vol]
Consumer Name Alpha Get Info
Cytokeratin 19, Spinal fluid

Part Model Get Info

  • Component
    Cytokeratin 19
    LP19423-0
    • Analyte
      Cytokeratin 19
      LP19423-0
      • Component Numerator
        Cytokeratin 19
        LP19423-0
        • Component Numerator Core
          Cytokeratin 19
          LP19423-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Cytokeratin 19:Hmotnostní koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:
de-DEGerman (Germany)Zytokeratin 19:Massenkonzentration:Zeitpunkt:Liquor:Quantitativ:
Synonyms: Cyfra 21-1; Zerebrospinalflüssigkeit
el-GRGreek (Greece)Κυτοκερατίνη 19:MCnc:Pt:ΕΝΥ:Qn:
Synonyms: CHEM MCnc Pt Qn ΕΝΥ Κυτοκερατίνη 19
es-ESSpanish (Spain)Citoqueratina 19:Concentración de masa:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Citoqueratina 19:Concentración de masa:Punto temporal:Fluído espinal cerebral:Cuantitativo:
et-EEEstonian (Estonia)Tsütokeratiin 19:MCnc:Pt:CSF:Qn:
Synonyms: Juhuslik Kvantitatiivne Liikvor
fr-CAFrench (Canada)Cytokératine 19:Concentration de masse:Temps ponctuel:LCR:Quantitatif:
fr-FRFrench (France)Cyfra 21:Masse/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-BEFrench (Belgium)Cytokératine 19:Concentration de masse:Temps ponctuel:LCR:Quantitatif:
it-ITItalian (Italy)Citocheratina 19:MCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Massa Liquido cerebrospinale Punto nel tempo (episodio)
nl-NLDutch (Netherlands)cytokeratine 19:massa/volume:moment:liquor cerebrospinalis:kwantitatief:
pl-PLPolish (Poland)Cytokeratyna 19:stężenie masowe:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:
ru-RURussian (Russian Federation)Цитокератин 19:МассКонц:ТчкВрм:ЦСЖ:Колич:
Synonyms: Количественный Массовая концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TRTurkish (Turkey)Sitokeratin 19:KütlKons:Zmlı:BOS:Kant:
zh-CNChinese (China)细胞角蛋白 19:质量浓度:时间点:脑脊液:定量型:
Synonyms: CK 19;Cyfra 21-1;细胞角蛋白-19 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 自身免疫型肝炎;自身免疫性肝炎

Example Units

UnitSource
ng/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=68928-1