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Part Description

LP135594-2   Heat shock protein 60 Ab
Heat shock proteins (HSP) are a class of functionally related proteins involved in the folding and unfolding of other proteins. Their expression is increased when cells are exposed to elevated temperatures or other stress. This increase in expression is transcriptionally regulated. The dramatic upregulation of the heat shock proteins is a key part of the heat shock response and is induced primarily by heat shock factor (HSF). HSPs are found in virtually all living organisms, from bacteria to humans.

Heat-shock proteins are named according to their molecular weight. For example, Hsp60, Hsp70 and Hsp90 (the most widely-studied HSPs) refer to families of heat shock proteins on the order of 60, 70 and 90 kilodaltons in size, respectively.

Hsp60 is involved in protein folding after its post-translational import to the mitochondrion/chloroplast.

HSP60 has been implicated in autoimmune disease as a result of its similarity to HSP65 of microorganisms. The development of antibodies against HSP60 has been hypothesized to trigger the ANCA response due to its corresponding homology to myeloperoxidase. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Heat shock protein 60 Ab:ACnc:Pt:Ser/Plas:Qn:IA
Long Common Name
Heat shock protein 60 Ab [Units/volume] in Serum or Plasma by Immunoassay
Short Name
HSP Ab SerPl IA-aCnc
Display Name
Heat shock protein 60 Ab IA Qn
Consumer Name Alpha Get Info
Heat shock protein 60 antibody, Blood

Part Model Get Info

  • Component
    Heat shock protein 60 Ab
    LP135594-2
    • Analyte
      Heat shock protein 60 Ab
      LP135594-2
      • Component Numerator
        Heat shock protein 60 Ab
        LP135594-2
        • Component Numerator Core
          Heat shock protein 60
          LP135698-1
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ACnc
    LP6773-8
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    IA
    LP217197-5

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.70 (MIN)
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Heat shock protein 60 (HSP60) Ab:Arbitrární koncentrace:Časový bod:Sérum/plazma:Kvantitativní:Imunoanalýza
el-GRGreek (Greece)Πρωτεΐνη θερμικού σοκ 60 Αντίσωμα:ACnc:Pt:Ορός/Πλάσμα:Qn:IA
Synonyms: ACnc IA Pt Qn SERO Αντίσωμα Ορός Ορός/Πλάσμα Πλάσμα Πρωτεΐνη Πρωτεΐνη θερμικού σοκ 60
es-ESSpanish (Spain)Proteína 60 de schok térmico Anticuerpos:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Proteína de choque térmico 60 Ab:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
fr-FRFrench (France)Protéine 60 du choc thermique Ac:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-ITItalian (Italy)Proteina heat shock 60 Ab:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)heat shock protein 60 As:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
pl-PLPolish (Poland)Białko szoku termicznego 60 Ab:stężenie w jednostkach umownych:punkt w czasie:surowica lub osocze:ilościowy:metoda immunologiczna
Synonyms: Białko szoku cieplnego60;HSP60 Przeciwciała do białka szoku cieplnego 60 (HSP60)
ru-RURussian (Russian Federation)Теплового шока протеин 60 Ат:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA
Synonyms: Антитело Белок Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Теплового шока белок 60 Точка во времени;Момент
tr-TRTurkish (Turkey)Isı şok protein 60 Ab:SçKons:Zmlı:Ser/Plaz:Kant:İA
Synonyms: Ak İmmünölçüm, immünoassay
zh-CNChinese (China)热休克蛋白 60 抗体:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ab;自身抗体 HSP60;HSP 60;HSP-60;Heat shock protein 60;热激蛋白 60 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

Example Units

UnitSource
[arb'U]/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=68934-9