68993-5

Human RNase P RNA [Presence] in Specimen by NAA with probe detection

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Term Description

Used as a control for determination of adequate human cells in clinical samples for viral testing

Part Description

LP135667-6 Human RNase P
Ribonuclease P (EC 3.1.26.5, RNase P) is a type of ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme - a ribonucleic acid that acts as a catalyst in the same way that a protein based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Further, RNase P is one of two known multiple turnover ribozymes in nature (the other being the ribosome), the discovery of which earned Sidney Altman and Thomas Cech the Nobel Prize in Chemistry in 1989: in the 1970s, Altman discovered the existence of precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA. Recent findings also reveal that RNase P has a new function. It has been shown that human nuclear RNase P is required for the normal and efficient transcription of various small noncoding RNAs, such as tRNA, 5S rRNA, SRP RNA and U6 snRNA genes., which are transcribed by RNA polymerase III, one of three major nuclear RNA polymerases in human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name: Human RNase P RNA:PrThr:Pt:XXX:Ord:Probe.amp.tar
Long Common Name: Human RNase P RNA [Presence] in Specimen by NAA with probe detection
Short Name: Human RNase P RNA Spec Ql NAA+probe
Display Name: Human RNase P RNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: Human RNase P, Specimen

Part Model Get Info

Component
Human Rnase P RNA
LP135666-8
- Analyte
  Human Rnase P RNA
  LP135666-8
  - Component Numerator
    Human Rnase P RNA
    LP135666-8
    - Component Numerator Core
      Human RNase P
      LP135667-6
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.38
Last Updated: Version 2.69 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
95422-2	Influenza virus A and B and SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection
101398-6	Monkeypox virus and Orthopoxvirus.non-variola DNA panel - Specimen

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Lidská ribonukleáza P RNA:Přítomnost nebo práh:Časový bod:XXX:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Humane RNase P RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ανθρώπινη RNase P RNA:PrThr:Pt:XXX:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: MICRO Ord P PrThr Pt RNA XXX Ανθρώπινη RNase P Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Rnase P humana RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN Rnasa P humana:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Ribonucléase P ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Rnasi P umana RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Humaan Rnase P RNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: probe.amp.tar
ru-RU	Russian (Russian Federation)	Человеческая РНКаза P РНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Human Rnaz P RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	人核糖核酸酶 P RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: P 型不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项人核酶 P;人 RNA P 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.