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Term Description

In the formula for the ROMA score, the HE4 is in units of pmol/L and the CA125 is in units of "U/ml". (Clinical Chemistry and Laboratory Medicine. Volume 49, Issue 3, Pages 521-525)
According to Abbott website, the formula can be used ONLY with results determined using the ARCHITECT method due to variability conferred by reagents/method. (http://www.abbottdiagnostics.com.au/Products/Instruments_by_Platform/roma.cfm#form).

Part Description

LP140230-6   Risk of ovarian malignancy algorithm score
The Risk of Ovarian Malignancy Algorithm (ROMA) is a qualitative serum test that combines the results of human epididymis protein 4 (HE4) by EIA, testing for cancer Ag 125 and the patient's menopausal status into a numerical score. The ROMA score is intended to aid in assessing whether a premenopausal or postmenopausal woman who presents with an ovarian adnexal mass is at a low or high likelihood of finding malignancy at surgery. ROMA is indicated for women who meet the following criteria: over age 18; ovarian adnexal mass present for which surgery is planned, and not yet referred to an oncologist. The ROMA score must be interpreted in conjunction with an independent clinical and radiological assessment. Source: LOINC partner 1

LOINC Names Get Info

Fully-Specified Name
Risk of ovarian malignancy algorithm score^premenopausal:Score:Pt:Ser/Plas:Qn:
Long Common Name
Risk of ovarian malignancy algorithm score in Serum or Plasma --premenopausal
Short Name
ROMA score premen SerPl
Display Name
Risk of ovarian malignancy algorithm score premenopausal [Score]
Consumer Name Alpha Get Info
Risk of ovarian malignancy algorithm score Premenopausal, Blood

Part Model Get Info

  • Component
    Risk of ovarian malignancy algorithm score^premenopausal
    LP307553-0
    • Analyte
      Risk of ovarian malignancy algorithm score
      LP140230-6
      • Component Numerator
        Risk of ovarian malignancy algorithm score
        LP140230-6
        • Component Numerator Core
          Risk of ovarian malignancy algorithm score
          LP140230-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      premenopausal
      LP140231-4
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Score
    LP185820-0
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
9029

Formula (Readable)

Premenopausal calculation = Predictive Index (PI) = -12.0 + 2.38 *LN(HE4) + 0.0626 * LN(CA125) ROMA = exp(PI) / [1 + exp(PI)] *10

Member of these Panels

LOINCLong Common Name
104551-7Ovarian malignancy (ROMA) panel - Serum or Plasma

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Ovariální malignita riziko skóre^Premenopauzální:Skóre:Časový bod:Sérum/plazma:Kvantitativní:
de-ATGerman (Austria)Synonyms: ROMA Index prämeno.
el-GRGreek (Greece)Βαθμολογία αλγορίθμου κινδύνου κακοήθειας ωοθηκών^προεμμηνοπαυσιακή:Βαθμολογία:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CHEM Pt Qn Βαθμολογία Βαθμολογία αλγορίθμου κινδύνου κακοήθειας ωοθηκών Κακοήθεια Ορός Ορός/Πλάσμα Πλάσμα προεμμηνοπαυσιακή
es-ESSpanish (Spain)Algoritmo de puntuación para el riesgo de malignidad ovárica^premenopausia:Puntuación:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Puntuación del algoritmo de riesgo de malignidad de ovario ^ premenopáusicas:Puntaje:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)Risque de malignité ovarienne score^Préménopause:Score:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Algoritmo di rischio di malignità ovarica, punteggio^pre menopausa:Punteggio:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Plasma prima di menopausa Punteggio di rischio di malignità ovarica Punto nel tempo (episodio) Siero Siero o Plasma
nl-NLDutch (Netherlands)risico voor ovariële maligniteit algoritmescore^premenopausaal:score:moment:serum of plasma:kwantitatief:
tr-TRTurkish (Turkey)Over malignansi algoritma skoru riski^premenopozal:Skor:Zmlı:Ser/Plaz:Kant:
Synonyms: Puan
zh-CNChinese (China)卵巢恶性肿瘤风险算法评分^绝经前:评分:时间点:血清/血浆:定量型:
Synonyms: 分值;分数;得分 分值;得分;分数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 卵巢恶性肿瘤风险算法评分（分数、分值、得分）;卵巢肿瘤风险算法评分 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 恶性程度;恶性肿瘤 时刻;随机;随意;瞬间 绝经期前;绝经前期的;绝经前期 血清或血浆

Example Units

UnitSource
{score}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=69569-2