70082-3
Interleukin 4 [Mass/volume] in Body fluid
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Part Descriptions
LP16472-0 Interleukin 4
Interleukin-4, abbreviated IL-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell.
It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Wikipedia
LP16472-0 Interleukin 4
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 4 is a 20,000 molecular weight glycoprotein originally called T Cell Growth Factor along with Interleukin 2. It is released primarily by activated T Cells and mast cells. Its primary target cells are T and B cells, macrophage/monocytes, and mast cells. Interleukin 4 activates B cell differentiation and immunoglobulins prior to action of Interleukin 6. It is also a co-stimulator along with anti-immunoglobulin antibodies of B cell proliferation. Interleukin 4 is bound to receptors located on activated T cells, resting and activated B cells, macrophages, and mast cells.
Source: Inter Science Institute,
Inter Science Institute
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Interleukin 4:
MCnc: Pt: Body fld: Qn: - Long Common Name
- Interleukin 4 [Mass/volume] in Body fluid
- Short Name
- Il4 Fld-mCnc
- Display Name
- Interleukin 4 (Body fld) [Mass/Vol]
- Consumer Name Alpha Get Info
- Interleukin 4, Body fluid
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Interleukin 4: |
| el-GR | Greek (Greece) | Ιντερλευκίνη 4: Synonyms: CHEM MCnc Pt Qn Ιντερλευκίνη 4 Σωματικό υγρό |
| es-ES | Spanish (Spain) | Interleukina 4: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Interleucina 4: |
| et-EE | Estonian (Estonia) | Interleukiin 4: Synonyms: Juhuslik Kehavedelik Kvantitatiivne |
| fr-CA | French (Canada) | Interleukine 4: |
| fr-FR | French (France) | Interleukine-4: |
| fr-BE | French (Belgium) | Interleukine 4: Synonyms: Il4 |
| it-IT | Italian (Italy) | Interleuchina 4: Synonyms: Chimica Concentrazione di Massa Liquido corporeo Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | interleukine 4: |
| pl-PL | Polish (Poland) | Interleukina 4: Synonyms: IL-4 |
| ru-RU | Russian (Russian Federation) | Интерлейкин 4: Synonyms: Количественный Массовая концентрация Тела жидкость Точка во времени; |
| tr-TR | Turkish (Turkey) | İnterlökin 4: |
| zh-CN | Chinese (China) | 白细胞介素 4: Synonyms: B 细胞刺激因子-1; |
Example Units
| Unit | Source |
|---|---|
| pg/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://