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Term Description

This test is used in the work up and management of hemochromatosis. Submitter's laboratory uses the method of MALDI-TOF with reference values recalculated from an ELISA method (see www.hepcidinanalysis.com).

Part Description

LP149244-8   Hepcidin 25 peptide
Hepcidin is a peptide hormone primarily synthesized in the liver and essential in regulating dietary iron absorption and distribution. Hepcidin lowers iron concentrations by counteracting the function of ferroportin, a major cellular iron exporter. Hepcidin forms include preprohormone (84 amino acids), prohormone (60 amino acids), and hormone (25 amino acids). Twenty- and 22-amino acid forms of Hepcidin also exist in the urine. The 25 amino acid form is referred to as the "bioactive" hepcidin since it can block the iron transporter ferroportin. The N terminal region is required for function and deletion of 5 N-terminal peptides results in a loss of function. Deficiency in hepcidin-25 concentration is associated with iron loading in hereditary hemochromatosis and thalassemia's. Source: Regenstrief LOINC

Reference Information

TypeSourceReference
WebcontentRegenstrief LOINCInformation on reference values for Hepcidin 25 amnio acid analysis. Hepcidin Analysis- Reference Values

LOINC Names Get Info

Fully-Specified Name
Hepcidin 25 peptide:SCnc:Pt:Ser/Plas:Qn:
Long Common Name
Hepcidin 25 amino acid peptide [Moles/volume] in Serum or Plasma
Short Name
Hepcidin-25 SerPl-sCnc
Display Name
Hepcidin 25 amino acid peptide [Moles/Vol]
Consumer Name Alpha Get Info
Hepcidin 25 amino acid peptide, Blood

Part Model Get Info

  • Component
    Hepcidin 25 peptide
    LP149244-8
    • Analyte
      Hepcidin 25 peptide
      LP149244-8
      • Component Numerator
        Hepcidin 25 peptide
        LP149244-8
        • Component Numerator Core
          Hepcidin 25 peptide
          LP149244-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)ببتيد الهيبسيدين المكون المكون من 25 حمض أمينيا في المصل أو البلازما ( بتقنية المولات / الحجم )
cs-CZCzech (Czechia)Hepcidin peptid o 25 aminokyselinách:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-ATGerman (Austria)Synonyms: Hepcidin-25
el-GRGreek (Greece)Πεπτίδιο εψιδίνη 25:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CHEM Pt Qn SCnc Ορός Ορός/Πλάσμα Πεπτίδιο εψιδίνη 25 Πλάσμα
es-ESSpanish (Spain)Hepcidina péptido 25:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Péptido de hepcidina 25:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)Hepcidine 1-25:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)Epdicina 25, peptide:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Peptide epdicina a 25 aminoacidi Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NLDutch (Netherlands)hepcidine-25-peptide:mol/volume:moment:serum of plasma:kwantitatief:
ru-RURussian (Russian Federation)Гепсидин 25 пептид:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Hepsidin 25 peptid:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CNChinese (China)铁调素 25 肽:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 缩氨酸 肝脏表达抗菌肽;Liver-Expressed Antimicrobial Peptide;LEAP-1;Hepcidin-25;铁调素-25;铁调素 25 氨基酸肽;铁调节蛋白 25;调节血液铁离子浓度的关键因子;炎症和血浆铁离子过多时增多;主要在肝脏内表达;属于脊椎动物家族中新的抗菌小肽;含有8个半胱氨酸残基和4个二硫键;具有显著的抗细菌和抗真菌活性;抗菌肽;Antibacterial Peptides;AMP;抗微生物肽;肽抗生素;鐵調素;铁调素 血清或血浆

Example Units

UnitSource
nmol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=71386-7