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Part Description

LP150268-3   t(15;17)(q24.1;q21.1)(PML,RARA)
The fusion of promyelocytic leukemia (PML, chromosome 15q24.1) and retinoic acid receptor alpha (RARA, chromosome 17q21.1) genes occurs due to a chromosomal translocation. The fused genes can be detected by various molecular techniques, including FISH and real-time quantitative polymerase chain reaction (RT-qPCR). The test is used to diagnose Acute Promyelocytic Leukemia (APL), detect residual or recurrent APL, and to monitor PML-RARA levels in patients with APL. The assay can be done on whole blood (plasma or cell-based) and bone marrow. Long, variant and/or short isoforms of PML-RARA fusion transcripts may be identified. The ratio of PML-RARA fusion transcript to a control gene (e.g. ABL1) may be reported for positive samples. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript:NRto:Pt:Bld/Tiss:Qn:Molgen
Long Common Name
t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method
Short Name
t(15;17)(PML,RARA)/control Bld/T
Display Name
t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(15;17)(q24.1;q21.1)(PML,RARA)/control Transcript, Blood or tissue specimen

Part Model Get Info

  • Component
    t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript
    LP287174-9
    • Analyte
      t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript
      LP287174-9
      • Component Numerator
        t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript
        LP229745-7
        • Component Numerator Core
          t(15;17)(q24.1;q21.1)(PML,RARA)
          LP150268-3
        • Component Numerator Core Suffix
          fusion transcript
          LP150217-0
      • Component Denominator
        control transcript
        LP150246-9
        • Component Denominator Core
          control transcript
          LP150246-9
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NRto
    LP6840-5
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Molgen
    LP6404-0

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
72104-3Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Fúzní transkript t(15;17)(q24.1;q21.1)(PML,RARA)/kontrolní transkript:Početní poměr:Časový bod:Krev/tkáň:Kvantitativní:Molekulární genetika
el-GRGreek (Greece)t(15;17)(q24.1;q21.1)(PML,RARA) μεταγραφή συγχώνευσης/μεταγραφή ελέγχου:NRto:Pt:Αίμα/Ιστός:Qn:Μοριακή γενετική
Synonyms: MOLPATH MOLPATH.TRNLOC NRto PML Pt Qn t(15;17)(q24.1;q21.1)(PML,RARA) Αίμα Αίμα/Ιστός Ιστός μεταγραφή ελέγχου μεταγραφή συγχώνευσης Μοριακή γενετική
es-ESSpanish (Spain)t(15;17)(q24.1;q21.1)(PML,RARA) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MXSpanish (Mexico)t (15; 17) (q24.1; q21.1) (PML, RARA) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FRFrench (France)t(15;17)(q24.1;q21.1)(PML,RARA) transcript de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CAFrench (Canada)t(15;17)(q24.1;q21.1)(PML,RARA) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-ITItalian (Italy)t(15,17)(q24.1,q21.1)(PML,RARA), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NLDutch (Netherlands)t(15;17)(q24.1;q21.1)(PML,RARA) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
ru-RURussian (Russian Federation)t(15;17)(q24.1;q21.1)(PML,RARA) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Промиелоцитарный лейкоз Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TRTurkish (Turkey)t(15;17)(q24.1;q21.1)(PML,RARA) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CNChinese (China)t(15;17)(q24.1;q21.1)(PML,RARA) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: MYL NR1B1 PML-1 PML-2 PML-3 PML-3B PML-X RAR alpha 型 RAR α型 RARalpha RARα 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 前髓细胞白血病 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 早幼粒细胞性白血病 早幼粒细胞白血病 早幼粒细胞白血病（Promyelocytic leukemia，PML） 时刻;随机;随意;瞬间 易位(15;17)(q24.1;q21.1)(PML,RARA) 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 视黄酸受体 alpha 视黄酸受体 alpha（Retinoic acid receptor alpha，RARA，RARalpha，RAR alpha） 视黄酸受体 α

Example Units

UnitSource
{ratio}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72274-4