72315-5

Platelet-derived growth factor receptor IgG Ab [Presence] in Serum or Plasma by Immunoassay

Active

Term Description

Platelet-derived growth factor receptor (PDGFR) IgG class autoantibodies can be detected by enzyme immunoassays. Results may be interpreted by humans or automated methods and used for the diagnosis of system sclerosis (SSc, diffuse and limited forms) and overlapping syndromes. This code was created for, but not limited to, the detection of PDGFR autoantibodies in Euroimmun's Systemic Sclerosis (Nucleoli) Profile EUROLINE (IgG) test kit.

Part Description

LP157266-0 Platelet-derived growth factor receptor
Antibodies to the platelet derived growth factor receptor (PDGFR) are a marker of systemic sclerosis. Anti-PDGFR antibodies activate the PDGFR and stimulate production of reactive oxygen species (ROS) and collagen. In contrast to normal PDGF receptor activation, which is typically short-lived, PDGFR antibodies cause persistent activation and therefore prolonged stimulation of ROS production and collagen overproduction, which leads to fibrosis. PMID: 18083509 Source: Regenstrief LOINC, PMID: 18083509

LOINC Names Get Info

Fully-Specified Name: Platelet-derived growth factor receptor Ab.IgG:PrThr:Pt:Ser/Plas:Ord:IA
Long Common Name: Platelet-derived growth factor receptor IgG Ab [Presence] in Serum or Plasma by Immunoassay
Short Name: PDGFR IgG SerPl Ql IA
Display Name: Platelet-derived growth factor receptor IgG IA Ql
Consumer Name Alpha Get Info: Platelet-derived growth factor receptor IgG antibody, Blood

Part Model Get Info

Component
Platelet-derived growth factor receptor Ab.IgG
LP157207-4
- Analyte
  Platelet-derived growth factor receptor Ab.IgG
  LP157207-4
  - Component Numerator
    Platelet-derived growth factor receptor Ab.IgG
    LP157207-4
    - Component Numerator Core
      Platelet-derived growth factor receptor
      LP157266-0
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IA
LP217197-5

Example Answer List: LL2206-2

Source: Estonian Society of Laboratory Medicine

Answer	Code	Score	Answer ID
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Borderline			LA4259-3
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Strong positive			LA18996-1

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Růstový faktor odvozený z trombocytů receptor IgG:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Imunoanalýza
de-AT	German (Austria)	Synonyms: PDGFR IgG AK
el-GR	Greek (Greece)	Υποδοχέας αιμοπεταλιακού αυξητικού παράγοντα Αντισώματα IgG:PrThr:Pt:Ορός/Πλάσμα:Ord:IA Synonyms: IA Ord PrThr Pt SERO Αιμοπετάλιο Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Ορός Ορός/Πλάσμα Πλάσμα Υποδοχέας αιμοπεταλιακού αυξητικού παράγοντα
es-ES	Spanish (Spain)	Receptor del factor de crecimiento derivado de plaquetas IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MX	Spanish (Mexico)	Receptor del factor de crecimiento derivado de plaquetas Ab.IgG:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
fr-FR	French (France)	PDGF récepteur Ac IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-IT	Italian (Italy)	Fattore di crescita derivato dalle piastrine, recettore Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA Synonyms: anticorpi IgG anticorpo Immunoassay Piastrine Plasma Presenza o Soglia Punto nel tempo (episodio) Recettore del fattore di crescita derivato dalle piastrine Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	Trombocyten-afgeleide groeifactorreceptor As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Receptor płytkopochodnego czynnika wzrostu Ab.IgG:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:metoda immunologiczna Synonyms: IgG Przeciwciała do receptora płytkopochodnego czynnika wzrostu przeciwciała IgG Przeciwciała IgG do receptora płytkopochodnego czynnika wzrostu
pt-BR	Portuguese (Brazil)	Plaqueta-derivada do fator de crescimento Ac.IgG:Limiar:Pt:Soro/Plas:Ord:Imunoensaio
ru-RU	Russian (Russian Federation)	Пластинок роста фактор рецептор Ат.IgG:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA Synonyms: Антитело Плазма Порядковый Рецептор к фактору роста, продуцируемому кровяными пластинками Сыворотка Сыворотка или Плазма Точка во времени;Момент Тромбоцит
tr-TR	Turkish (Turkey)	Trombositten-türeyen büyüme faktörü reseptörü Ab.IgG:MevcEşik:Zmlı:Ser/Plaz:Srl:İA Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	血小板衍生生长因子受体抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 Platelet-derived growth factor receptor;PDGF-R;血小板衍生性生长因子受体;血小板源生长因子受体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 因素存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间系数血栓细胞血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.