72318-9

Centromere protein A IgG Ab [Presence] in Serum or Plasma by Immunoassay

Active

Term Description

Centromere protein A (CENP-A) IgG class autoantibodies can be detected by enzyme immunoassays. Results may be interpreted by humans or automated methods and used for the diagnosis of system sclerosis (SSc, diffuse and limited forms) and overlapping syndromes. This code was created for, but not limited to, the detection of CENP-A autoantibodies in Euroimmun's Systemic Sclerosis (Nucleoli) Profile EUROLINE (IgG) test kit.

Part Description

LP157222-3 Centromere protein A
Centromere protein A (CENP-A) is an essential centromere protein encoded by the CENPA gene. Overexpression of CENP-A causes chromosomal aberrations, and depletion of CENP-A promotes apoptosis and induces cell cycle arrest. Overexpression of CENP-A has been associated with high grade cancers and is a prognostic factor for patients with estrogen receptor (ER)-positive breast cancer. Antibodies to CENP-A are associated with scleroderma, systemic sclerosis, CREST syndrome, and other rheumatologic diseases. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Centromere protein A Ab.IgG:PrThr:Pt:Ser/Plas:Ord:IA
Long Common Name: Centromere protein A IgG Ab [Presence] in Serum or Plasma by Immunoassay
Short Name: CENP A IgG SerPl Ql IA
Display Name: Centromere protein A IgG IA Ql
Consumer Name Alpha Get Info: Centromere Protein A IgG antibody, Blood

Part Model Get Info

Component
Centromere protein A Ab.IgG
LP157212-4
- Analyte
  Centromere protein A Ab.IgG
  LP157212-4
  - Component Numerator
    Centromere protein A Ab.IgG
    LP157212-4
    - Component Numerator Core
      Centromere protein A
      LP157222-3
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IA
LP217197-5

Example Answer List: LL2206-2

Source: Estonian Society of Laboratory Medicine

Answer	Code	Score	Answer ID
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
Borderline			LA4259-3
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
Strong positive			LA18996-1

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
85092-5	Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Centromera protein A IgG:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Imunoanalýza
de-AT	German (Austria)	Synonyms: CENP-A-IgG-AK ql.
el-GR	Greek (Greece)	Πρωτεΐνη κεντρομερούς Α Αντισώματα IgG:PrThr:Pt:Ορός/Πλάσμα:Ord:IA Synonyms: A IA Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Κεντρομερίδιο Ορός Ορός/Πλάσμα Πλάσμα Πρωτεΐνη Πρωτεΐνη κεντρομερούς Α
es-ES	Spanish (Spain)	Proteína A del centrómero (CENP-A) IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MX	Spanish (Mexico)	Centrómero de proteína A Ab.IgG:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
fr-FR	French (France)	Centromère protéine A Ac IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-IT	Italian (Italy)	Centromero, proteina A Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA Synonyms: anticorpi IgG anticorpo Immunoassay Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	centromeereiwit A As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Białko centromerowe A Ab.IgG:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:metoda immunologiczna Synonyms: CENP-A IgG Przeciwciała do białka centromerowego A przeciwciała IgG Przeciwciała IgG do antygenu A Przeciwciała IgG do białka centromerowego A
pt-BR	Portuguese (Brazil)	Proteína A do Centrômero Ac.IgG:Limiar:Pt:Soro/Plas:Ord:Imunoensaio
ru-RU	Russian (Russian Federation)	Центромерный протеин A Ат.IgG:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA Synonyms: Антитело Белок Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Sentromer protein A Ab.IgG:MevcEşik:Zmlı:Ser/Plaz:Srl:İA Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	着丝粒蛋白 A 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法 Synonyms: A IgG A 型 A 型抗体 Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CRST 综合征;着丝粒;动粒 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间着丝点蛋白 A;centromere protein A;CENP-A;CENPA 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.