Version 2.78

Term Description

IgG antibodies to HLA class II antigens (DP, DQ, and DR) can be detected by flow cytometry in serum of pre and post-transplant organ recipients. A positive result is an indication of a sensitization to HLA antigens. This code is based on, but not exclusive to, the submitter's test kit, One Lambda's FlowPRA Screening Test, which uses beads coated with common and rare purified HLA Class I or II antigens.
Source: Regenstrief LOINC

Part Description

LP156721-5   HLA-DP+DQ+DR Ab.IgG
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.

Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens. Source: Regenstrief LOINC

Fully-Specified Name

Component
HLA-DP+DQ+DR Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Flow cytometry

Additional Names

Short Name
HLA-DP+DQ+DR IgG Ser Ql FC
Display Name
HLA-DP+DQ+DR (class II) IgG FC Ql (S)
Consumer Name Alpha Get Info
HLA-DP+DQ+DR (class II) IgG antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
HLA
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94428-0 HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC)
94440-5 HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC)
72905-3 Neutrophil Ab and HLA Ab screen panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) HLA-DP+DQ6DR IgG:PrThr:Punto temporal:Suero:Ord:Citometria de flujo (FC)
es-MX Spanish (Mexico) HLA-DP + DQ + DR Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Citometría de flujo (FC)
et-EE Estonian (Estonia) HLA-DP+DQ+DR antikehad.IgG:PrThr:Pt:S:Ord:Voolutsütomeetria
Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum
fr-CA French (Canada) HLA-DP+DQ+DR, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Cytométrie de flux
fr-FR French (France) HLA-DP+DQ+DR anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Cytométrie de flux
fr-BE French (Belgium) HLA-DP+DQ+DR Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal:Cytométrie de flux
Synonyms: Anticorps
it-IT Italian (Italy) HLA-DP+DQ+DR Ab.IgG:PrThr:Pt:Siero:Ord:Citometria a flusso
Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Presenza o Soglia Pressione differenziale Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) HLA-DP+DQ+DR As.IgG:aanwezigheid:moment:serum:ordinaal:flowcytometrie
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) HLA-DP+DQ+DR Ac.IgG:Limiar:Pt:Soro:Ord:Citometria de fluxo
ru-RU Russian (Russian Federation) HLA-DP+DQ+DR Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:Проточная цитометрия
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) HLA-DP+DQ+DR Ab.IgG:MevcEşik:Zmlı:Ser:Srl:Akış sitometri
Synonyms: Ak Ak.IgG Akış hücremetresi Mevcut
zh-CN Chinese (China) HLA-DP+DQ+DR 抗体.IgG:存在情况或阈值:时间点:血清:序数型:流式细胞测量术
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 HLA II 类;II 类 HLA HLA 抗原;人类白细胞抗原;human leukocyte antigen HLA-DP+DQ+DR Ab 人白细胞抗原 人类白细胞抗原 人类白细胞抗原(Human Leukocyte Antigen,HLA) 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 动态 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术(Flow Cytometry,FC);流式细胞计 白细胞抗原

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