72385-8

2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) [Mass/volume] in Saliva (oral fluid) by Confirmatory method

Active

Part Descriptions

LP35885-0 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
EDDP (2-ethylidene-1,5-dimethyl1-3,3-diphenylpyrrolidine) is a primary metabolite of methadone, a synthetic opioid used for the treatment of opioid dependence. It is excreted in bile and urine along with other another methadone metabolite, EMPD. Levels of methadone itself are variable and depend on a patient's urine pH value, dose given, and metabolism. EDDP levels are less variable and can be detected 4 to 6 hours after methadone use, therefore, EDDP is preferentially used to check for methadone exposure. Source: Regenstrief Institute

LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine:MCnc:Pt:Saliva:Qn:Confirm
Long Common Name: 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Short Name: EDDP Sal Cfm-mCnc
Display Name: 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) Confirm (Sal) [Mass/Vol]
Consumer Name Alpha Get Info: 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP), Saliva

Part Model Get Info

Component
2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
LP35885-0
- Analyte
  2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
  LP35885-0
  - Component Numerator
    2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
    LP35885-0
    - Component Numerator Core
      2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
      LP35885-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Saliva
LP7565-7
- System Core
  Saliva
  LP7565-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Confirm
LP6197-0

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 9591

Member of these Panels

LOINC	Long Common Name
72476-5	Methadone panel - Saliva (oral fluid) by Confirmatory method

Member of these Groups Get Info

LOINC Group	Group Name
LG37661-2	2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine\|ANYProp\|ANYTm\|ANYSys\|ANYMeth

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	2-ethyliden-1,5-dimethyl-3,3-difenylpyrrolidin (EDDP):Hmotnostní koncentrace:Časový bod:Sliny:Kvantitativní:Konfirmace
el-GR	Greek (Greece)	2-αιθυλιδενο-1,5-διμεθυλο-3,3-διφαινυλοπυρρολιδίνη:MCnc:Pt:Σίελος:Qn:Επιβεβαίωση Synonyms: 2-αιθυλιδενο-1,5-διμεθυλο-3,3-διφαινυλοπυρρολιδίνη DRUG/TOX MCnc Pt Qn Επιβεβαίωση Σίελος
es-ES	Spanish (Spain)	2-etilideno-1,5-dimetil-3,3-difenilpirrolidina (EDDP):Concentración de masa:Punto temporal:Saliva:Qn:Confirmatorio Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	2-etiliden-1,5-dimetil-3,3-difenilpirrolidina:Concentración de masa:Punto temporal:Saliva:Cuantitativo:Confirmar
et-EE	Estonian (Estonia)	2-etüülideen-1,5-dimetüül-3,3-difenüülpürolidiin:MCnc:Pt:Sal:Qn:Kinnitav Synonyms: Juhuslik Kvantitatiivne Sülg
fr-CA	French (Canada)	2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP):Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Confirmation
fr-FR	French (France)	2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine:Masse/Volume:Ponctuel:Salive:Numérique:Confirmation
fr-BE	French (Belgium)	2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP):Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Confirmé
it-IT	Italian (Italy)	2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina:MCnc:Pt:Saliva:Qn:Conferma Synonyms: 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina (ED Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	2-ethylideen-1,5-dimethyl-3,3-difenylpyrrolidine:massa/volume:moment:speeksel:kwantitatief:bevestiging
pl-PL	Polish (Poland)	2-Etylideno-1,5-Dimetylo-3,3-Difenylopirolidyna:stężenie masowe:punkt w czasie:ślina:ilościowy:potwierdzenie Synonyms: metoda potwierdzenia
ru-RU	Russian (Russian Federation)	2-Этилиден-1,5-Диметил-3,3-Дифенил Пирролидин:МассКонц:ТчкВрм:Слюна:Колич:Подтверждать Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	2-Etiliden-1,5-Dimetil-3,3-Difenilpirrolidin:KütlKons:Zmlı:Tükürük:Kant:Onay Synonyms: Teyid
zh-CN	Chinese (China)	2-亚乙基-1,5-二甲基-3,3-四氢吡咯:质量浓度:时间点:唾液:定量型:毒理学确认试验 Synonyms: Ⅰ 2-乙叉-1,5-二甲基-3,3-吡咯烷;2-乙叉-1,5-二甲基-3,3-四氢吡咯;2-乙叉-1,5-二甲基-3,3-氮戊环;2-亚乙基-1,5-二甲基-3,3-吡咯烷;2-亚乙基-1,5-二甲基-3,3-氮戊环;美沙酮代谢产物 Ⅱ Ⅲ I II III 三叁可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 津;津液;涎确认方法;确认法;确认试验药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ng/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.