72725-5
t(11;14)(q13.2;q32)(MYEOV,IGH) fusion transcript [Identifier] in Blood or Tissue by FISH Nominal
Active
Term Description
Labs may report the X number of cells that have the translocation, t(11;14)(q13.2;q32), out of Y number of cells (e.g. 80 out of 100 cells, or 80%). Results are typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format.
Source: Regenstrief LOINC
Part Descriptions
LP157587-9 t(11;14)(q13.2;q32)(MYEOV,IGH)
Probes specific for MYEOV/IGH t(11;14)(q13.2;q32) are used to detect the reciprocal translocation commonly associated with multiple myeloma (MM) and resulting in an up-regulation of cyclin D1 (CCND1). The MYEOV gene is 360 kb from the CCND1 gene, which is also involved chromosomal rearrangements resulting in human cancers. Patients with MM who have t(11;14)(q13.2;q32) are predicted to have an aggressive clinical course.
Source: Regenstrief LOINC
LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues.
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Source: Wikipedia, FISH
Fully-Specified Name
- Component
- t(11;14)(q13.2;q32)(MYEOV,IGH) fusion transcript
- Property
- Prid
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Nom
- Method
- FISH
Additional Names
- Short Name
- t(11;14)(MYEOV,IGH) Bld/T FISH
- Display Name
- t(11;14)(q13.2;q32)(MYEOV,IGH) fusion transcript FISH Nom (Bld/Tiss)
- Consumer Name Alpha Get Info
- t(11;14)(q13.2;q32)(MYEOV,IGH) fusion transcript analysis, Blood or tissue specimen
Example Answer List: LL2352-4
Source: Regenstrief LOINC| Answer | Code | Score | Answer ID |
|---|---|---|---|
| (11q13,14q32)x2[100] Normal result. No nuclei contain t(11;14) MYEOV/IGH |
LA19539-8 | ||
| t(11;14)(q13;q32)[67]/(11q13,14q32)x2[33] Pathological result. 67% nuclei include t(11;14) MYEOV/IGH |
LA19540-6 |
Basic Attributes
- Class
- MOLPATH.TRNLOC
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.61
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | t(11; |
| es-MX | Spanish (Mexico) | t (11; |
| fr-CA | French (Canada) | t(11; |
| fr-FR | French (France) | t(11; |
| it-IT | Italian (Italy) | t(11; Synonyms: Ibridazione in situ fluorescente (FISH) Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
| nl-NL | Dutch (Netherlands) | t(11; |
| pl-PL | Polish (Poland) | t (11; Synonyms: Translokacja (11; |
| pt-BR | Portuguese (Brazil) | t(11; |
| tr-TR | Turkish (Turkey) | t(11; |
| zh-CN | Chinese (China) | t(11; Synonyms: Fluorescent in situ hybridization; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=72725-5
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright