Version 2.78

Part Descriptions

LP172561-5   Ceftolozane+Tazobactam
Ceftolozane/tazobactam is a first-line IV therapy for the treatment of certain serious Gram-negative bacterial infections, including those caused by multi-drug resistant Pseudomonas aeruginosa. Source: Regenstrief LOINC

LP172561-5   Ceftolozane+Tazobactam
Ceftolozane is a cephalosporin with powerful activity against Gram-negative bacteria including Pseudomonas aeruginosa and Enterobacteriaceae.[http://aac.asm.org/content/57/4/1577.full] Tazobactam is a beta lactamase inhibitor and penicillin derivative that is effective against beta-lactamase-producing bacteria.[PubChem: 123630] Ceftolozane blocks penicillin binding proteins which disrupts bacterial cell-wall synthesis that leads to bacterial cell death. When tazobactam is added to ceftolozane, there is a broader spectrum of antimicrobial activity against resistant strains including extended spectrum beta-lactamases (ESBLs).Tazobactam prevents class A beta-lactamases and some class C beta-lactamases from hydrolyzing ceftolozane. Together, ceftolozane+tazobactam are an effective treatment for complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired bacterial pneumonia, and ventilator-associated bacterial pneumonia. PMID: 25516692 Source: Regenstrief LOINC

Fully-Specified Name

Component
Ceftolozane+Tazobactam
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
Agar diffusion

Additional Names

Short Name
Ceftolozane+Tazobactam Islt KB
Display Name
Ceftolozane+Tazobactam Disk diffusion (KB) [Susc]
Consumer Name Alpha Get Info
Susceptibility to Ceftolozane+Tazobactam

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
8278

Member of these Panels

LOINC Long Common Name
50546-1 Bacterial susceptibility panel by Disk diffusion (KB)

Member of these Groups Get Info

LOINC Group Group Name
LG41460-3 Ceftolozane+TazobactamSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Ceftolozan+Tazobactam:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Agardiffusionstest
es-ES Spanish (Spain) Ceftolozane+Tazobactam:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Difusión en disco; Kirby Bauer
es-MX Spanish (Mexico) Ceftolozano + Tazobactam:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Difusión de disco (KB)
fr-FR French (France) Ceftolozane+tazobactam:Sensibilité:Ponctuel:Isolat:Alphanumérique:Diffusion gel Agar
it-IT Italian (Italy) Ceftolozane+Tazobactam:Susc:Pt:Isolato:OrdQn:Agar diffusione
Synonyms: Disco diffusione (KB) Kirby-Bauer Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) ceftolozaan + tazobactam:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:agardiffusie
pt-BR Portuguese (Brazil) Ceftolozana+Tazobactam::Pt:Isolado:OrdQn:Difusão em agar (disco)
tr-TR Turkish (Turkey) Seftolozan+Tazobaktam:Duyr:Zmlı:İzolat:SrlKant:Agar difüzyon
zh-CN Chinese (China) 头孢洛林+他唑巴坦:抗生素敏感性:时间点:分离株:定量型或序数型:琼脂扩散法
Synonyms: 3a-甲基-7-氧代-3b-(1H-1,2,3,-三唑-1-亚甲基)-4-硫杂-1-氮杂双环[3.2.0]庚烷-2a-羧酸4，4-二氧化物;他左巴坦;他巴克坦;青霉烷砜类 Beta-内酰胺酶抑制剂;青霉烷砜类β-内酰胺酶抑制剂 KB 法;Kirby-bauer 法;平皿扩散;平皿扩散法;琼脂平皿扩散;琼脂平皿扩散法;琼脂扩散;琼脂板扩散;琼脂板扩散法 三唑巴坦 分离物;分离菌;分离菌株;隔离种群 头孢洛林（头孢洛林酯、头孢他诺林、头孢他洛林酯、头孢他洛林）+他唑巴坦（他左巴坦、他巴克坦） 巴坦 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73647-0