73841-9
Tetrahydrodeoxycortisol [Moles/volume] in Urine
Active
Part Description
LP15884-7 Tetrahydrodeoxycortisol
Tetrahydrodeoxycortisol (THS) is a mineralocorticoid the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approximately 5% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4%) and the T-allele of the -344 C/T polymorphism of CYP11B2 is more strongly associated with higher THS levels than the C-allele. PMID: 16984984, PMID: 15522937, PMID: 15272911.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Tetrahydrodeoxycortisol
Fully-Specified Name
- Component
- Tetrahydrodeoxycortisol
- Property
- SCnc
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Tetrahydrodeoxycortisol [Moles/volume] in Urine
- Short Name
- TH-DC Ur-sCnc
- Display Name
- Tetrahydrodeoxycortisol (U) [Moles/Vol]
- Consumer Name Alpha Get Info
- Tetrahydrodeoxycortisol, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.44
- Last Updated
- Version 2.44 (MIN)
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG37125-8 | Tetrahydrodeoxycortisol| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Τετραϋδροδεοξυκορτιζόλη: Synonyms: SCnc Τετραϋδροδεοξυκορτιζόλη |
es-ES | Spanish (Spain) | Tetrahidrodesoxicortisol: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Tetrahidrodesoxicortisol: |
et-EE | Estonian (Estonia) | Tetrahüdrodeoksükortisool: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Uriin |
fr-FR | French (France) | Tétrahydro-11-déoxycortisol: |
it-IT | Italian (Italy) | Tetraidrodeossicortisolo: Synonyms: Chimica Concentrazione di Sostanza Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | tetrahydrodeoxycortisol: |
pt-BR | Portuguese (Brazil) | Tetrahidrodeoxicortisol: |
ru-RU | Russian (Russian Federation) | Тетрагидродеоксикортизол: Synonyms: Количественный Молярность; |
tr-TR | Turkish (Turkey) | Tetrahidrodeoksikortizol: |
zh-CN | Chinese (China) | 四氢脱氧皮质醇: Synonyms: TH-DC; |
Example Units
Unit | Source |
---|---|
umol/L | Example UCUM Units |
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