73910-2

PAX8 Ag [Presence] in Tissue by Immune stain

Active

Term Description

The result of this cytology stain is usually included as part of, or as an addenda to, a pathology report to aid in interpretation.

Part Descriptions

LP172780-1 PAX8 Ag
PAX8 is a member of the paired box (PAX) family of transcription factors, which play critical roles during fetal development and cancer growth. PAX8 is a transcription factor for genes exclusively expressed the thyroid cell type, maintaining the functional differentiation of such cell. Defect in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2. PAX8 is also involved in kidney cell differentiation and has been shown to be expressed in three of the most common types of renal cell carcinoma: clear cell, chromophobe and papillary carcinoma. Source: Regenstrief LOINC

LP172781-9 PAX8
Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene, a member of the paired box (PAX) family of transcription factors. The PAX8 nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. It also functions in very early stages of kidney organogenesis. Mutations in the PAX8 gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, PAX8

LOINC Names Get Info

Fully-Specified Name: PAX8 Ag:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name: PAX8 Ag [Presence] in Tissue by Immune stain
Short Name: PAX8 Ag Tiss Ql ImStn
Display Name: PAX8 Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info: PAX8 antigen, Tissue

Part Model Get Info

Component
PAX8 Ag
LP172780-1
- Analyte
  PAX8 Ag
  LP172780-1
  - Component Numerator
    PAX8 Ag
    LP172780-1
    - Component Numerator Core
      PAX8
      LP172781-9
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Immune stain
LP6333-1

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.44
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 17984

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	PAX8 Ag:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GR	Greek (Greece)	PAX8 Αντιγόνο:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση Synonyms: Ord PATH PAX8 PrThr Pt Ανοσολογική χρώση Αντιγόνο Ιστός
es-ES	Spanish (Spain)	PAX8 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	PAX8 Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
fr-FR	French (France)	PAX8 Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-IT	Italian (Italy)	PAX8, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica Synonyms: Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NL	Dutch (Netherlands)	PAX8 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring Synonyms: antigeen
ru-RU	Russian (Russian Federation)	PAX8 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	PAX8 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama Synonyms: Antijen Mevcut
zh-CN	Chinese (China)	PAX8 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法 Synonyms: Ag PAX-8;XPax8;配对盒基因 8;Paired box gene 8;转录因子配对盒家族成员;转录因子 PAX 家族成员;member of the paired box (PAX) family of transcription factors;PAX8 核蛋白;PAX8 核内蛋白;PAX8 nuclear protein 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染法染色方法染色法着色着色方法着色法

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73910-2

Third Party Copyright

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.