Version 2.73

73910-2PAX8 Ag [Presence] in Tissue by Immune stainActive

Term Description

The result of this cytology stain is usually included as part of, or as an addenda to, a pathology report to aid in interpretation.
Source: Regenstrief LOINC

Part Descriptions

LP172780-1   PAX8 Ag
PAX8 is a member of the paired box (PAX) family of transcription factors, which play critical roles during fetal development and cancer growth. PAX8 is a transcription factor for genes exclusively expressed the thyroid cell type, maintaining the functional differentiation of such cell. Defect in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2. PAX8 is also involved in kidney cell differentiation and has been shown to be expressed in three of the most common types of renal cell carcinoma: clear cell, chromophobe and papillary carcinoma. Source: Regenstrief LOINC

LP172781-9   PAX8
Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene, a member of the paired box (PAX) family of transcription factors. The PAX8 nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. It also functions in very early stages of kidney organogenesis. Mutations in the PAX8 gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, PAX8

Fully-Specified Name

Immune stain

Additional Names

Short Name
PAX8 Ag Tiss Ql ImStn
Display Name
PAX8 Ag Immune stain Ql (Tiss)
Consumer Name Alpha
PAX8 antigen, Tissue

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.44
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Common US Lab Results Rank

Language Variants Get Info

zh-CNChinese (China)
PAX8 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (Netherlands)
PAX8 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
fr-FRFrench (France)
PAX8 antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (Italy)
PAX8 , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
pt-BRPortuguese (Brazil)
PAX8 Ag::Pt:Tecido:Ord:Imunocoloração
ru-RURussian (Russian Federation)
PAX8 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-MXSpanish (Mexico)
PAX8 Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
es-ESSpanish (Spain)
PAX8 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (Turkey)
PAX8 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info