74037-3
Transmissible spongiform encephalopathy [Identifier] in Brain by Light microscopy
Active
Term Description
Specific histopathologic exam without immunostain to identify and classify TSE (Scrapie, CWE, and BSE). Findings on light microscopy (plaques, neuronal loss, etc.) indicate the disease process, which is used to classify the disease.
Source: Regenstrief LOINC
Part Description
LP173528-3 Transmissible spongiform encephalopathy
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions (encephalopathies) that affect the brain and nervous system of many animals, including humans. According to the most widespread hypothesis they are transmitted by abnormal prions, though some other data suggest an involvement of a Spiroplasma infection. Mental and physical abilities deteriorate and a myriad of tiny holes appear in the cortex causing it to appear like a sponge (hence spongiform) when brain tissue obtained at autopsy is examined under a microscope. The disorders cause impairment of brain function, including memory changes, personality changes and problems with movement that worsen over time. Most TSEs are sporadic and occur in animals. Prion diseases of animals in include classical bovine spongiform encephalopathy (BSE) (C-type), atypical (H or L-type) BSE, Scrapie, atypical scrapie, Nor98, and chronic wasting disease (CWE). H-type and L-type BSE were named based on abnormal prion bands migrating to a higher (H) or lower (L) position on western blot analysis compared to the classical BSE (C-type) prion protein. Prion diseases of humans include classic Creutzfeldt-Jakob disease, new variant Creutzfeldt-Jakob disease (nvCJD, a human disorder related to Bovine spongiform encephalopathy), Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia and kuru. These conditions form a spectrum of diseases with overlapping signs and symptoms.
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Source: Wikipedia, Transmissible spongiform encephalopathy
Fully-Specified Name
- Component
- Transmissible spongiform encephalopathy
- Property
- Prid
- Time
- Pt
- System
- Brain
- Scale
- Nom
- Method
- Microscopy.light
Additional Names
- Short Name
- TSE Brain Micro
- Display Name
- Transmissible spongiform encephalopathy LM Nom (Brain)
- Consumer Name Alpha Get Info
- Transmissible spongiform encephalopathy, Brain
Example Answer List: LL2535-4
Source: American Association of Veterinary Laboratory Diagnosticians| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Bovine spongiform encephalopathy (BSE) - C type Classical BSE (C type) |
LA20104-8 | ||
| Atypical Bovine spongiform encephalopathy (BSE) - H or L type H or L type BSE |
LA20105-5 | ||
| Scrapie | LA20108-9 | ||
| Atypical scrapie | LA20109-7 | ||
| Nor98 | LA20111-3 | ||
| Chronic wasting disease (CWD) | LA20110-5 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.46
- Last Updated
- Version 2.46
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Transmissible spongiforme Enzephalopathie: |
| es-ES | Spanish (Spain) | Encefalopatía espongiforme transmisible: |
| es-MX | Spanish (Mexico) | Encefalopatía espongiforme transmisible: |
| fr-CA | French (Canada) | Encéphalopathie spongiforme transmissible: |
| it-IT | Italian (Italy) | Encefalopatie spongiformi trasmissibili: Synonyms: Microbiologia Microscopia ottica Presenza o Identità Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | overdraagbare spongiforme encefalopathie: Synonyms: lichtmicroscopie |
| pt-BR | Portuguese (Brazil) | Encefalopatia espongiforme transmissível: |
| ru-RU | Russian (Russian Federation) | Трансмиссивная губчатая энцефалопатия: Synonyms: Номинальный; |
| tr-TR | Turkish (Turkey) | Bulaşan spongiform ensefalopati: |
| zh-CN | Chinese (China) | 传染性海绵状脑病: Synonyms: 光学显微镜方法; |
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- CodeSystem lookup
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