74122-3

Ubiquitin Ag [Presence] in Tissue by Immune stain

Active

Term Description

Detects the presence of intracellular ubiquitinated filamentous inclusions in the periphery of senile plaques and neurofibrillary tangles in Alzheimer disease and lewy bodies in Parkinsion disease.
Source: Regenstrief LOINC

Part Description

LP173629-9   Ubiquitin
Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. There are four genes in the human genome that produce ubiquitin; UBB, UBC, UBA52 and RPS27A. Immunohistochemistry using antibodies to ubiquitin can identify abnormal accumulations of this protein inside cells, indicating a disease process. These protein accumulations are referred to as inclusion bodies (which is a general term for any microscopically visible collection of abnormal material in a cell). Examples include neurofibrillary tangles in Alzheimer disease, lewy body in Parkinson disease, pick bodies in Pick's disease, and inclusions in motor neuron disease and Huntington disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia

Fully-Specified Name

Component

Ubiquitin Ag

Property

PrThr

Time

Pt

System

Tiss

Scale

Ord

Method

Immune stain

Additional Names

Short Name

Ubiquitin Ag Tiss Ql ImStn

Display Name

Ubiquitin Ag Immune stain Ql (Tiss)

Consumer Name Alpha Get Info

Ubiquitin antigen, Tissue

Example Answer List: LL360-9

Basic Attributes

Class

PATH

Type

Laboratory

First Released

Version 2.46

Last Updated

Version 2.56

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Language Variants Get Info

Related Names

• Antigen
• Antigens
• IHC
• Imm
• Immunohistochemical stain
• Immunostain
• ImStn
• Imun
• Imune
• Ordinal
• PATHOLOGY
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• St
• Stains
• Stn
• Tissue
• Tissue, unspecified

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74122-3

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