74122-3
Ubiquitin Ag [Presence] in Tissue by Immune stain
Active
Term Description
Detects the presence of intracellular ubiquitinated filamentous inclusions in the periphery of senile plaques and neurofibrillary tangles in Alzheimer disease and lewy bodies in Parkinsion disease.
Part Description
LP173629-9 Ubiquitin
Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. There are four genes in the human genome that produce ubiquitin; UBB, UBC, UBA52 and RPS27A. Immunohistochemistry using antibodies to ubiquitin can identify abnormal accumulations of this protein inside cells, indicating a disease process. These protein accumulations are referred to as inclusion bodies (which is a general term for any microscopically visible collection of abnormal material in a cell). Examples include neurofibrillary tangles in Alzheimer disease, lewy body in Parkinson disease, pick bodies in Pick's disease, and inclusions in motor neuron disease and Huntington disease.
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Source: Wikipedia
Fully-Specified Name
- Component
- Ubiquitin Ag
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Immune stain
Additional Names
- Long Common Name
- Ubiquitin Ag [Presence] in Tissue by Immune stain
- Short Name
- Ubiquitin Ag Tiss Ql ImStn
- Display Name
- Ubiquitin Ag Immune stain Ql (Tiss)
- Consumer Name Alpha Get Info
- Ubiquitin antigen, Tissue
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.46
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Ουβικιτίνη Αντιγόνο: Synonyms: PrThr Ουβικιτίνη |
| es-ES | Spanish (Spain) | Ubiquitina Antígeno: |
| es-MX | Spanish (Mexico) | Ubiquitin Ag: |
| fr-FR | French (France) | Ubiquitine antigène: |
| it-IT | Italian (Italy) | Ubiquitina, Ag: Synonyms: Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & |
| nl-NL | Dutch (Netherlands) | ubiquitine Ag: Synonyms: antigeen |
| pt-BR | Portuguese (Brazil) | Ubiquitina Ag: |
| ru-RU | Russian (Russian Federation) | Убихитин Аг: Synonyms: Порядковый Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | Ubikitin Ag: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 泛素 抗原: Synonyms: Ag 依次型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=74122-3
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
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LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://