LOINC
Version 2.67

74125-6Mesothelin Ag [Presence] in Tissue by Immune stainActive

Part Description

LP173611-7   Mesothelin
Mesothelin, or MSLN, is a40 kDa protein that is encoded by the MSLN gene. It is present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The protein was first identified by its reactivity with monoclonal antibody K1. Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mesothelin

Fully-Specified Name

Component
Mesothelin Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
Mesothelin Ag Tiss Ql ImStn
Display Name
Mesothelin Ag Immune stain Ql (Tiss)

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.46
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
间皮素 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (NETHERLANDS)
mesotheline Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
fr-FRFrench (FRANCE)
Mésothéline antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (ITALY)
Mesotelina , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
pt-BRPortuguese (BRAZIL)
ru-RURussian (RUSSIAN FEDERATION)
Мезотелин Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-ESSpanish (SPAIN)
Mesotelina Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (TURKEY)
Mezsotelin Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74125-6