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Term Description

Percent genomic homology between a new isolated PRRS virus strain and a PPRS vaccine strain (e.g. Lelystad, Fostera, IngelvacMLV or IngelvacATP) is based on the number of matching amino acids per total amino acids sequenced in the open reading frame 5 (ORF5) gene. The more homologous the ORF5 gene sequences, the more closely the variants are related. It is thought that sequence homology between isolates and vaccines will predict vaccine efficacy, however this is currently debated since little is known about the immune response to PRRS virus.

Part Descriptions

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP174583-7   Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Fostera
Porcine reproductive and respiratory syndrome virus (PRRSV), also referred to as Blue-Ear Pig disease, causes significant disease and can lead to reproductive failures such as weak fetuses, mummified fetuses, abortions or still borns. PRRSV is an RNA virus and belongs to the order Nidovirales, family Arteriviridae and the genus Arterivirus. PRRSV is spread among all ages of pigs and herds through direct and indirect contact. PRRSV is considered one of the most economically important infectious agents in the swine industry worldwide. The continual changing genomic characteristics of the various strains of this virus make testing of herds an important part of disease management. PMID: 26646630 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Fostera:NFr:Pt:Isolate:Qn:Sequencing
Long Common Name
PRRSV ORF5 gene sequence homology to Fostera in Isolate by Sequencing
Short Name
PRRSV Fostera Hmlgy Islt Seq-NFr
Display Name
PRRSV ORF5 gene sequence homology to Fostera Sequencing (Isol)
Consumer Name Alpha Get Info
PRRSV ORF5 gene Sequence Homology to Fostera

Part Model Get Info

  • Component
    Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Fostera
    LP174583-7
    • Analyte
      Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Fostera
      LP174583-7
      • Component Numerator
        Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Fostera
        LP174583-7
        • Component Numerator Core
          Porcine reproductive and respiratory syndrome virus ORF5 gene sequence homology to Fostera
          LP174583-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Sequencing
    LP150045-5

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.46
Last Updated
Version 2.64 (MIN)
Change Reason
Abbreviated "Porcine reproductive and respiratory syndrome virus" to "PRRSV" in the Long Common Name. PRRSV is shorter and more commonly used in test names.
Order vs. Observation
Both

Formula (Readable)

(#of matching amino acids/total amino acids sequenced)*100 = % homology

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)PRRSV ORF5 genová sekvence homologie s Fostera:Početní podíl:Časový bod:Izolát:Kvantitativní:Sekvenace
el-GRGreek (Greece)Ομολογία αλληλουχίας του γονιδίου ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων με το Fostera:NFr:Pt:Απομονωμένο στέλεχος:Qn:Αλληλούχιση
Synonyms: MICRO NFr Pt Qn Αλληλουχία γονιδίου ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Αλληλούχιση Απομονωμένο στέλεχος Γονίδιο Γονίδιο ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ιός Ιός του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων Ομολογία αλληλουχίας του γονιδίου ORF5 του ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων με το Fostera Των χοίρων
es-ESSpanish (Spain)Gen ORF5 del virus del síndrome reproductivo y respiratorio porcino homología de secuencia con Fostera:Fracción numérica:Punto temporal:Aislado:Qn:Secuenciación
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Homología de secuencia del gen ORF5 del virus del síndrome respiratorio y reproductivo porcino con Fostera:Fracción numérica:Punto temporal:Aislado:Cuantitativo:Secuenciación
it-ITItalian (Italy)Virus della sindrome riproduttiva e respiratoria del suino, sequenziamento del gene ORF5 a Fostera:NFr:Pt:Isolato:Qn:Sequenziamento
Synonyms: Frazione numerica Gene ORF5 virus PRRS Microbiologia Punto nel tempo (episodio) Sequenziamento del gene ORF5 a Fostera virus PRRS Sequenziamento del gene ORF5 virus PRRS Virus PRRS
nl-NLDutch (Netherlands)'porcine' reproductief en respiratoir syndroomvirus ORF5-gensequentie homologie met Fostera:getalsfractie:moment:isolaat:kwantitatief:sequencing
Synonyms: porcine voortplantings- en respiratoir syndroom virus van varken; PRRSV
pl-PLPolish (Poland)Wirus zespołu rozrodczo-oddechowego świń homologia sekwencji genu ORF5 do Fostera:frakcja liczbowa:punkt w czasie:izolat:ilościowy:sekwencjonowanie
Synonyms: Gen ORF5 PRRSV Sekwencja genu ORF5 PRRSV Sekwencja homologiczna genu ORF5 PRRSV do szczepu Foster
tr-TRTurkish (Turkey)Porsin reprodüktif ve respiratuvar sendrom virüs ORF5 gen dizisi Fostera ile homoloji:SayFr:Zmlı:İzolat:Kant:Sekanslama
Synonyms: Dizi tayini
zh-CNChinese (China)猪生殖与呼吸综合征病毒 ORF5 基因序列 Fostera 同源物:计数型分数:时间点:分离株:定量型:序列测定
Synonyms: Lelystad 病毒;PRRS;SIRSV;兰耳病;新猪病;母猪后期流产;猪不育和呼吸综合症;猪不育和呼吸综合症（Swine infertility and respiratory syndrome，SIRSV）;猪生殖与呼吸系统综合症;猪生殖与呼吸综合症（Porcine reproductive and respiratory syndrome，PRRS）;猪繁殖与呼吸综合征;猪蓝耳病;猪蓝色病;神秘仔猪病;神秘猪病;莱利斯塔猪病毒（Lelystad Virus，LV）;蓝耳猪病;蓝耳病;蓝色流产症 PRRSV;猪生殖呼吸综合征病毒;猪呼吸繁殖综合征病毒;猪繁殖与呼吸道综合征病毒;猪繁殖和呼吸障碍综合征;Porcine Reproductive and Respiratory Syndrome;PRRS;蓝耳病;Blue Ear Disease;可译框架;可读框;开放阅读框;开放读码框;开放读码框架;编码框;ORF;open reading frame 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 猪生殖与呼吸综合征病毒 ORF5 基因序列同源物 相对于 Fostera;相对于 Fostera 的猪生殖与呼吸综合征病毒 ORF5 基因序列同源物;PRRSV;猪生殖呼吸综合征病毒;猪呼吸繁殖综合征病毒;猪繁殖与呼吸道综合征病毒;猪繁殖和呼吸障碍综合征;Porcine Reproductive and Respiratory Syndrome;PRRS;蓝耳病;Blue Ear Disease;可译框架;可读框;开放阅读框;开放读码框;开放读码框架;编码框;ORF;open reading frame 猪的 猪科 猪科的 遗传基因;遗传因子;吉恩;生物基因

Example Units

UnitSource
%Example UCUM Units

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74306-2