74414-4

Varicella zoster virus IgM Ab [Units/volume] in Body fluid by Immunoassay

Active

Term Description

Quantitative analysis of varicella-zoster virus (VZV) IgM antibodies in body fluid (e.g. mother's milk, lachrymal liquid, aqueous humor, etc.). This term is based on, but not limited in use to, The LIAISON® VZV IgM assay uses chemiluminescence immunoassay (CLIA) technology for the quantitative determination of specific IgM antibodies to VZV.

Part Descriptions

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.http://jvi.asm.org/content/88/24/13936.full In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.https://grose.lab.uiowa.edu/vzv-genomes-and-evolution Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

LP7238-1   Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

Varicella zoster virus Ab.IgM:ACnc:Pt:Body fld:Qn:IA

Long Common Name

Varicella zoster virus IgM Ab [Units/volume] in Body fluid by Immunoassay

Short Name

VZV IgM Fld IA-aCnc

Display Name

VZV IgM IA Qn (Body fld)

Consumer Name Alpha Get Info

Varicella zoster virus (VZV; Chickenpox) IgM antibody, Body fluid

Part Model Get Info

• Component

  Varicella zoster virus Ab.IgM
  LP40113-0

  • Analyte

    Varicella zoster virus Ab.IgM
    LP40113-0

    • Component Numerator

      Varicella zoster virus Ab.IgM
      LP40113-0

      • Component Numerator Core

        Varicella zoster virus
        LP14853-3

      • Component Numerator Core Suffix

        Ab.IgM
        LP32403-5

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  ACnc
  LP6773-8

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Body fld
  LP7238-1

  • System Core

    Body fld
    LP7238-1

  • Super System

    NULL
     

• Scale

  Qn
  LP7753-9

• Method

  IA
  LP217197-5

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.46

Last Updated

Version 2.56 (MIN)

Change Reason

The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Arbitrary concentration
• Autoantibodies
• Autoantibody
• B/F
• BF
• bod
• Bodies
• Body fluid
• Body fluid, unsp
• Chicken pox
• Chicken pox virus
• Chickenpox
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• Fl
• Fld
• FLU
• Fluid
• Herpes zoster
• HHV-3
• Human herpesvirus 3
• IAA
• ID
• Immune globulin M
• Immunoglobulin M
• Infectious Disease
• InfectiousDisease
• MEIA
• Microbiology
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Shingles
• SUDS
• VZ
• VZV
• Zoster

Example Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74414-4

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.