Version 2.80

Part Description

LP29040-0   Complement total hemolytic CH50
Complement total hemolytic CH50 testing is used to monitor Systemic Lupus Erythematosus (SLE) patients' response to therapy. It is also used to evaluate complement component deficiency, complement activity in patients with immune complexes , glomerulonephritis, rheumatoid arthritis, and cryoglobulinemia. Complement is a system of 25 proteins associated with cell membranes and present in plasma; it plays a vital role in the function of the immune system. Complement components function in the "classical" and "alternative" pathways. The CH50 assay mainly evaluates the classical pathway. Complement proteins are activated during the acute phase of inflammation or infection. Decreased levels of complement components occur during hypercatabolism, expenditure in immune complexes or due to hereditary deficiency. Decreasing complement levels may signal upcoming clinical problems, especially lupus nephritis. Source: Regenstrief Institute

Fully-Specified Name

Component
Complement total hemolytic CH50 actual/normal
Property
RelACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Long Common Name
Complement total hemolytic CH50 actual/normal in Serum by Immunoassay
Short Name
CH50 Act/Nor Ser IA
Display Name
Complement total hemolytic CH50 actual/normal IA (S) [Rel units/Vol]
Consumer Name Alpha Get Info
Complement Total Hemolytic CH50 actual/normal, Blood

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.58 (MIN)
Change Reason
Updated term to align with existing complement activity terms and clarify that findings are based on actual/normal results.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
74519-0 Complement activity panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ολικό αιμολυτικό συμπλήρωμα CH50 πραγματικό/φυσιολογικό:RelACnc:Pt:Ορός:Qn:IA
Synonyms: RelACnc Ολικό αιμολυτικό συμπλήρωμα Ολικό αιμολυτικό συμπλήρωμα CH50
es-ES Spanish (Spain) Complemento hemolitico total CH50 actual/normal:Concentración arbitraria relativa:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Complemento de CH50 hemolítico total actual / Normal:Concentración relativa arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Komplemendi klassikalise tee aktiivsus CH50 seerumis tegelik/normaalne:RelACnc:Pt:S:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Seerum Suhteline kokkuleppeline kontsentratsioon
fr-CA French (Canada) Complément hémolytique total CH50, Mesuré/normal:Concentration relative arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) Complément total hémolytique CH50 Patient (%):Activité arbitraire relative:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE French (Belgium) Hémolyse CH50 Mesuré/normal:Concentration relative arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Mesuré/normal
it-IT Italian (Italy) Complemento emolitico totale CH50 effettivo/normale:RelACnc:Pt:Siero:Qn:IA
Synonyms: Concentrazine Arbitraria Relativa Ematologia (coagulazione) conta differenziale Immunoassay Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) complement totaal hemolytisch CH50 gemeten/normaal:relatieve eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: gemeten/normaal IA
pt-BR Portuguese (Brazil) Complemento funcional atividade caminho clássico::Pt:Soro:Qn:Imunoensaio
ru-RU Russian (Russian Federation) Комплемент общий гемолитический CH50 актуальный/нормальный:ОтнПроизвКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Количественный Относительная произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Kompleman total hemolitik CH50 gerçek/normal:GörSçKons:Zmlı:Ser:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 补体总溶血活性 Ch50 实际的/正常的:相对任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 全体数量 全部 共计 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实测值 实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值 实测的 实际值 对照 对照标准 对照物 对照的 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 正常的 汇总 相对任意浓度;相对型任意浓度;相对人工型浓度 血液学/细胞计数;血液学与细胞计数

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74521-6