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Term Description

This test measures the hydroxyproline level in children who have been diagnosed with maple syrup urine disease are on a therapeutic diet for their condition. Dried blood spot specimens are sent to the lab for monitoring tests periodically. Depending on the lab, the hydroxyproline level may be used in combination with leucine, isoleucine and/or alloisoleucine levels to monitor the patient's progress.

Part Descriptions

LP15650-2   Hydroxyproline
4-Hydroxyproline, or hydroxyproline (C 5 H 9 O 3 N), is an uncommon amino acid, abbreviated as HYP. Hydroxyproline differs from proline by the presence of a hydroxyl (OH) group attached to the C (gamma) atom.

Proline hydroxylation requires ascorbic acid (vitamin C). The most obvious, first effects (gingival and hair problems) of absence of ascorbic acid in humans come from the resulting defect in hydroxylation of proline residues of collagen, with reduced stability of the collagen molecule, causing scurvy.
Increased serum and urine levels of hydroxyproline have also been demonstrated in Paget's disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hydroxyproline (Wikipedia)

LP15650-2   Hydroxyproline
Hydroxyproline is a hydrophilic amino acid with uncharged polar groups and is a major component of collagen. Increased with hydroxyprolinemia and iminoglycinuria. Decreased with chronic Vitamin C deficiency. (Information from ARUP Laboratories 9/14/06) Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name
Hydroxyproline^post therapeutic diet:SCnc:Pt:Bld.dot:Qn:
Long Common Name
Hydroxyproline [Moles/volume] in DBS --post therapeutic diet
Short Name
OH-Proline p diet DBS-sCnc
Display Name
Hydroxyproline post therapeutic diet (DBS) [Moles/Vol]
Consumer Name Alpha Get Info
Hydroxyproline after Therapeutic Diet, Dried blood spot

Part Model Get Info

  • Component
    Hydroxyproline^post therapeutic diet
    LP306211-6
    • Analyte
      Hydroxyproline
      LP15650-2
      • Component Numerator
        Hydroxyproline
        LP15650-2
        • Component Numerator Core
          Hydroxyproline
          LP15650-2
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      post therapeutic diet
      LP174563-9
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Bld.dot
    LP21304-8
    • System Core
      Bld.dot
      LP21304-8
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.61 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
74874-9Metabolic disorder therapy monitoring panel - DBS

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Hydroxyprolin^Po terapeutické dietě:Látková koncentrace:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
el-GRGreek (Greece)Υδροξυπρολίνη^κατόπιν θεραπευτικής διατροφής:SCnc:Pt:Bld.dot:Qn:
Synonyms: Bld.dot CHAL Pt Qn SCnc Αίμα Δίαιτα κατόπιν θεραπευτικής διατροφής Υδροξυπρολίνη
es-ESSpanish (Spain)Hidroxiprolina^post dieta terapéutica:Concentración de sustancia:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Hidroxiprolina ^ dieta posterapéutica:Concentración de sustancias:Punto temporal:DBS:Cuantitativo:
fr-FRFrench (France)Hydroxyproline^après régime thérapeutique:Moles/Volume:Ponctuel:Sang buvard:Numérique:
it-ITItalian (Italy)Idrossiprolina^dieta post terapia:SCnc:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Concentrazione di Sostanza Punto nel tempo (episodio) Sangue Spot sangue secco Test di provocazione
nl-NLDutch (Netherlands)hydroxyproline^na therapeutisch dieet:mol/volume:moment:gedroogde bloedspot:kwantitatief:
ru-RURussian (Russian Federation)Гидроксипролин^после терапевтической диеты:МолКонц:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Количественный Кровь Кровь сухая капля Молярность;Молярная объёмная концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)Hidroksiprolin^terapötik diyet snr:SubKons:Zmlı:Kan.nokta:Kant:
zh-CNChinese (China)羟基脯氨酸^在治疗性饮食之后:物质的量浓度:时间点:全血.斑点:定量型:
Synonyms: Hyp;OH-脯氨酸;羟脯氨酸 XXX刺激 - 在...之后 之后于... 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 时刻;随机;随意;瞬间 治疗 治疗性的 治疗性饮食之后;之后于治疗性饮食;在治疗性饮食（治疗膳食、治疗饮食、治疗用饮食、食饵疗法饲料、疗用饲粮）之后 治疗的 疗效饮食;食饵疗法饲料;治疗膳食;治疗饮食 血;血液 饮食;日常饮食;日常食物;规定饮食;食谱

Example Units

UnitSource
umol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74880-6