74953-1
Macroprolactin [Units/volume] in Serum or Plasma
Active
Part Description
LP34987-5 Macroprolactin
Monomeric prolactin is the most common form of circulating prolactin. Prolactin also has several isoforms, including the dimeric form ("big-prolactin") that has a molecular weight of ~50 kD and polymeric form ("big-big prolactin") that has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302
Source: Regenstrief LOINC,
Fully-Specified Name
- Component
- Macroprolactin
- Property
- ACnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Macroprolactin [Units/volume] in Serum or Plasma
- Short Name
- Macroprolactin SerPl-aCnc
- Display Name
- Macroprolactin Qn
- Consumer Name Alpha Get Info
- Macroprolactin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.48
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17709
Member of these Panels
LOINC | Long Common Name |
---|---|
78993-3 | Prolactin isoforms panel - Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Macroprolactina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Macroprolactina: |
et-EE | Estonian (Estonia) | Makroprolaktiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Macroprolactine: |
fr-FR | French (France) | Macroprolactine: |
fr-BE | French (Belgium) | Macroprolactine: |
it-IT | Italian (Italy) | Macroprolattina: Synonyms: Chimica Concentrazione Arbitraria Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | macroprolactine: |
pt-BR | Portuguese (Brazil) | Macroprolactina: |
ru-RU | Russian (Russian Federation) | Макропролактин: Synonyms: Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Makroprolaktin: |
zh-CN | Chinese (China) | 巨催乳素: Synonyms: bbPRL; |
Example Units
Unit | Source |
---|---|
[arb'U]/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=74953-1
LOINC Copyright
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