74976-2

Phenytoin [Mass/volume] in Serum or Plasma --trough

Active

Part Descriptions

LP14732-9 Phenytoin
An anticonvulsant that is used to treat a wide variety of seizure disorders. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its side effects and interactions with other drugs. [MeSH 2014: Phenytoin] Source: National Library of Medicine, MeSH 2006, MeSH: Phenytoin

LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LOINC Names Get Info

Fully-Specified Name: Phenytoin^trough:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Phenytoin [Mass/volume] in Serum or Plasma --trough
Short Name: Phenytoin Trough SerPl-mCnc
Display Name: Phenytoin trough [Mass/Vol]
Consumer Name Alpha Get Info: Phenytoin trough, Blood

Part Model Get Info

Component
Phenytoin^trough
LP308007-6
- Analyte
  Phenytoin
  LP14732-9
  - Component Numerator
    Phenytoin
    LP14732-9
    - Component Numerator Core
      Phenytoin
      LP14732-9
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  trough
  LP20176-1
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.48
Last Updated: Version 2.48 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
78439-7	Phenytoin free and total trough panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG51075-6	Phenytoin^trough\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fenytoin^Údolní koncentrace:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Φαινυτοΐνη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn ελάχιστα επίπεδα Ορός Ορός/Πλάσμα Πλάσμα Φαινυτοΐνη
es-MX	Spanish (Mexico)	Fenitoína ^ comedero:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES	Spanish (Spain)	Fenitoína^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Fenütoiin^baas:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Phénytoïne^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Diphénylhydantoïne^taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Phénytoïne^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif: Synonyms: Minimum, nadir
it-IT	Italian (Italy)	Fenitoina^valore minimo:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL	Dutch (Netherlands)	fenytoïne^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
ru-RU	Russian (Russian Federation)	Фенитоин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Fenitoin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant: Synonyms: çukur düzey
zh-CN	Chinese (China)	苯妥英^波谷:质量浓度:时间点:血清/血浆:定量型: Synonyms: C15H12N2O2;二苯乙内酰脲;苯妥营;二苯基乙内酰脲;二苯尿囊素一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
mg/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.