Version 2.80

Part Descriptions

LP14732-9   Phenytoin
An anticonvulsant that is used to treat a wide variety of seizure disorders. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its side effects and interactions with other drugs. [MeSH 2014: Phenytoin] Source: National Library of Medicine, MeSH 2006 , MeSH: Phenytoin

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
Phenytoin^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Phenytoin [Mass/volume] in Serum or Plasma --trough
Short Name
Phenytoin Trough SerPl-mCnc
Display Name
Phenytoin trough [Mass/Vol]
Consumer Name Alpha Get Info
Phenytoin trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.48 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
78439-7 Phenytoin free and total trough panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG51075-6 Phenytoin^trough|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Φαινυτοΐνη^ελάχιστα επίπεδα:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: MCnc Φαινυτοΐνη
es-MX Spanish (Mexico) Fenitoína ^ comedero:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Fenitoína^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Fenütoiin^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Phénytoïne^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Diphénylhydantoïne taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Phénytoïne^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Fenitoina^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) fenytoïne^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Fenítoina^basal::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Фенитоин^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Fenitoin^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 苯妥英^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: C15H12N2O2;二苯乙内酰脲;苯妥营;二苯基乙内酰脲;二苯尿囊素 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
mg/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74976-2