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Term Description

Bacterial identification by MALDI-TOF (matrix-assisted laser desorption ionization time of flight) is a diagnostic test for identifying the specific organism(s) responsible for a bacterial infection. MALDI-TOF is a form of mass spectrometry that analyzes the proteins contained in an isolated bacterial colony. The resulting mass spectrum is compared to a reference database of bacterial protein mass spectra in order to identify the organism(s) present in the test sample. This term was created for, but is not limited in use to, the Bruker Daltonics MALDI Biotyper CA System, which is indicated for use in diagnosing Gram-negative bacterial infections.

Part Descriptions

LP14082-9   Bacteria
One of the three domains of life (the others being Eukarya and Archaea), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls and multiply by cell division. They exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to oxygen (aerobic, anaerobic, or facultatively anaerobic) and by how they obtain their energy (chemotrophic, i.e. via a chemical reaction or phototrophic, via a light reaction). In addition, chemotrophs obtain their energy from chemicals, lithotrophic from inorganic compounds and organotrophic from organic compounds. Bacteria are also classified by the source carbon that they utilize: heterotrophic, from organic sources or autotrophic, from carbon dioxide. They can also be classified by whether or not they stain (based on the structure of their cell walls) with crystal violet dye: gram-negative or gram-positive. Source: National Library of Medicine, MeSH 2006

LP186074-3   MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373 Source: Regenstrief LOINC, PMID: 23824373

LOINC Names Get Info

Fully-Specified Name
Bacteria:Prid:Pt:Isolate:Nom:MS.MALDI-TOF
Long Common Name
Bacteria identified in Isolate by MS.MALDI-TOF
Short Name
Bacteria Islt MS.MALDI-TOF
Display Name
Bacteria identified MS.MALDI-TOF Nom (Isol)
Consumer Name Alpha Get Info
Bacterial test

Part Model Get Info

  • Component
    Bacteria
    LP14082-9
    • Analyte
      Bacteria
      LP14082-9
      • Component Numerator
        Bacteria
        LP14082-9
        • Component Numerator Core
          Bacteria
          LP14082-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    MS.MALDI-TOF
    LP186074-3

Example Answer List: LL2991-9

Source: New York State Health (Wadsworth Center)
AnswerCodeScoreAnswer ID
Escherichia coliCopyright http://snomed.info/sct ID:112283007 Escherichia coli (organism)LA21335-7
Klebsiella pneumoniaeLA21336-5
Salmonella spLA21368-8
Pseudomonas aeruginosaLA19340-1
Enterobacter cloacaeLA21369-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.50
Last Updated
Version 2.78 (NAM)
Change Reason
Release 2.78: COMPONENT: Removed "Identified" from the component because it is implied by the Property "Prid";
Order vs. Observation
Both
Common Test Rank Get Info
13359

Member of these Panels

LOINCLong Common Name
97324-8Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
97326-3Staphylococcus aureus identification and resistance panel by Molecular genetics method

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Bakterie:Přítomnost nebo identita:Časový bod:Izolát:Nominální:Hmotnostní spektrometrie.MALDI-TOF
de-DEGerman (Germany)Bakterien:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:MS.MALDI-TOF
Synonyms: Matrix-assisted laser desorption/ionization - Time-of-Flight-Massenspektrometrie
el-GRGreek (Greece)Βακτήριο:Prid:Pt:Απομονωμένο στέλεχος:Nom:MS.MALDI-TOF
Synonyms: MICRO MS.MALDI-TOF Nom Prid Pt Απομονωμένο στέλεχος Βακτήριο
es-ESSpanish (Spain)Bacteria:Presencia o identidad:Punto temporal:Aislado:Nom:MS.MALDI-TOF
es-MXSpanish (Mexico)Bacterias identificadas:Presencia o identidad:Punto temporal:Aislado:Nominal:SRA. MALDI-TOF
fr-FRFrench (France)Bactérie:Identification:Ponctuel:Isolat:Résultat nominal:Spectrométrie MALDI-TOF
it-ITItalian (Italy)Batteri:Prid:Pt:Isolato:Nom:MS.MALDI-TOF
Synonyms: Microbiologia Presenza o Identità Punto nel tempo (episodio)
nl-NLDutch (Netherlands)bacteriën:identificator:moment:isolaat:nominaal:MALDI-TOF
Synonyms: bacterie massaspectometrie; Malditof
pl-PLPolish (Poland)Bakterie:obecność lub identyfikacja:punkt w czasie:izolat:skala nominalna:spektrometria mas.MALDI-TOF
Synonyms: wynik kategorialny
zh-CNChinese (China)细菌:存在与否或特征标识:时间点:分离株:名义型:MS.MALDI-TOF
Synonyms: 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基质辅助激光解吸/电离飞行时间质谱;基质辅助激光解吸电离飞行时间质谱;基质辅助激光解吸飞行时间质谱;基质辅助激光解析电离飞行时间质谱;Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry;MALDI-TOF-MS;Matrix-assisted laser desorption ionization-time of flight 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 细菌类;菌

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75756-7