Version 2.80

Term Description

The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone.

Fully-Specified Name

Component
Breast cancer 10Y risk of distant recurrence score
Property
Score
Time
Pt
System
^Patient
Scale
Qn
Method
Calculated.Prosigna

Additional Names

Long Common Name
Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna
Short Name
Brst ca 10Y dist recur score Prosigna
Display Name
Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna [Score]
Consumer Name Alpha Get Info
Breast cancer 10-year risk of distant recurrence score

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73 (MIN)
Change Reason
Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.
Order vs. Observation
Both
Common Test Rank Get Info
17578

Formula (Readable)

Calculated using a Cox model that includes coefficients for the gene expression assay results, proliferation score, and gross tumor size.

Member of these Panels

LOINC Long Common Name
76546-1 Breast cancer 10-year risk of distant recurrence panel by Prosigna

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κίνδυνος απομακρυσμένης υποτροπής του καρκίνου του μαστού σε 10 έτη:Βαθμολογία:Pt:^Ασθενής:Qn:Υπολογιζόμενο.Prosigna
Synonyms: Βαθμολογία Καρκίνος Κίνδυνος απομακρυσμένης υποτροπής του καρκίνου του μαστού σε 10 έτη
es-ES Spanish (Spain) Ratio del riesgo de recurrencia a 10 años en el cáncer de mama:Puntuación:Punto temporal:^paciente:Qn:Calculado por Prosigna
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Puntuación de riesgo de recidiva a distancia de 10 años de cáncer de mama:Puntaje:Punto temporal:^ Paciente:Cuantitativo:Calculado por Prosigna
fr-FR French (France) Cancer du sein score des risques de récidive sur 10 ans:Score:Ponctuel:Patient:Numérique:Test Prosigna calcul
it-IT Italian (Italy) Tumore della mammella, rischio 10 anni di recidive tumorali, punteggio:Punteggio:Pt:^Paziente:Qn:Calcolato.Prosigna
Synonyms: Calcolato mediante Prosigna Patologia molecolare paziente Punto nel tempo (episodio)
zh-CN Chinese (China) 乳腺癌远处转移 10 年风险评分:评分:时间点:^患者:定量型:计算法.Prosigna
Synonyms: Prosigna 法 乳腺癌远处转移（远程转移） 10 年风险（危险性、风险性、危险）评分;乳腺（乳房）肿瘤 分值;分数;得分 分值;得分;分数 分子病理学;分子病理学试验 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 癌 计算;计算型方法

Example Units

Unit Source
{score} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76544-6