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Term Description

The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone.

LOINC Names Get Info

Fully-Specified Name
Breast cancer 10Y risk of distant recurrence score:Score:Pt:^Patient:Qn:Calculated.Prosigna
Long Common Name
Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna
Short Name
Brst ca 10Y dist recur score Prosigna
Display Name
Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna [Score]
Consumer Name Alpha Get Info
Breast cancer 10-year risk of distant recurrence score

Part Model Get Info

  • Component
    Breast cancer 10Y risk of distant recurrence score
    LP188450-3
    • Analyte
      Breast cancer 10Y risk of distant recurrence score
      LP188450-3
      • Component Numerator
        Breast cancer 10Y risk of distant recurrence score
        LP188450-3
        • Component Numerator Core
          Breast cancer 10Y risk of distant recurrence score
          LP188450-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Score
    LP185820-0
  • Time
    Pt
    LP6960-1
  • System
    ^Patient
    LP310005-6
    • System Core
      NULL
       
    • Super System
      Patient
      LP6985-8
  • Scale
    Qn
    LP7753-9
  • Method
    Calculated.Prosigna
    LP189620-0

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73 (MIN)
Change Reason
Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.
Order vs. Observation
Both
Common Test Rank Get Info
17578

Formula (Readable)

Calculated using a Cox model that includes coefficients for the gene expression assay results, proliferation score, and gross tumor size.

Member of these Panels

LOINCLong Common Name
76546-1Breast cancer 10-year risk of distant recurrence panel by Prosigna

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Karcinom prsu skóre 10letého rizika vzdálené recidivy:Skóre:Časový bod:^Pacient:Kvantitativní:Vypočteno pomocí testu Prosigna
el-GRGreek (Greece)Κίνδυνος απομακρυσμένης υποτροπής του καρκίνου του μαστού σε 10 έτη:Βαθμολογία:Pt:^Ασθενής:Qn:Υπολογιζόμενο.Prosigna
Synonyms: - MOLPATH Prosigna Pt Qn Ασθενής Βαθμολογία Καρκίνος Κίνδυνος απομακρυσμένης υποτροπής του καρκίνου του μαστού σε 10 έτη Υπολογιζόμενο Υπολογιζόμενο.Prosigna
es-ESSpanish (Spain)Ratio del riesgo de recurrencia a 10 años en el cáncer de mama:Puntuación:Punto temporal:^paciente:Qn:Calculado por Prosigna
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Puntuación de riesgo de recidiva a distancia de 10 años de cáncer de mama:Puntaje:Punto temporal:^ Paciente:Cuantitativo:Calculado por Prosigna
fr-FRFrench (France)Cancer du sein score des risques de récidive sur 10 ans:Score:Ponctuel:^patient:Numérique:Test Prosigna calcul
it-ITItalian (Italy)Tumore della mammella, rischio 10 anni di recidive tumorali, punteggio:Punteggio:Pt:^Paziente:Qn:Calcolato.Prosigna
Synonyms: Calcolato mediante Prosigna Patologia molecolare paziente Punto nel tempo (episodio)
zh-CNChinese (China)乳腺癌远处转移 10 年风险评分:评分:时间点:^患者:定量型:计算法.Prosigna
Synonyms: Prosigna 法 乳腺癌远处转移（远程转移） 10 年风险（危险性、风险性、危险）评分;乳腺（乳房）肿瘤 分值;分数;得分 分值;得分;分数 分子病理学;分子病理学试验 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 癌 计算;计算型方法

Example Units

UnitSource
{score}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76544-6